Results 311 to 320 of about 516,976 (376)

Neutrophils in cancer: At the crucial crossroads of anti‐tumor and pro‐tumor

Cancer Communications, EarlyView.
Abstract Neutrophils are important components of the immune system and play a key role in defending against pathogenic infections and responding to inflammatory cues, including cancer. Their dysregulation indicates potential disease risk factors. However, their functional importance in disease progression has often been underestimated due to their ...
Wenpeng Cai, Tao Fan, Chu Xiao, Ziqin Deng, Yixiao Liu, Chunxiang Li, Jie He   +6 more
wiley   +1 more source

EEG-based graph network analysis in relation to regional tau in asymptomatic Alzheimer's disease. [PDF]

Brain Commun
Spruyt L, Mlinarič T, Dusart N, Reinartz M, Meade G, Van Hulle MM, Van Laere K, Dupont P, Vandenberghe R.   +8 more
europepmc   +1 more source

Serotonergic modulators in Alzheimer's disease: a hope in the hopeless condition

Chemistry &Biodiversity, Accepted Article.
Alzheimer disease (AD) is the main cause of dementia worldwide. AD is a progressive brain neurodegenerative disease due to genetic and environmental factors that induce a progressive accumulation of intracellular hyperphosphorylated tau protein and extracellular amyloid protein (Aβ).
Ali I. Al-Gareeb, Morkoss Fakhry, Ali K. Albuhadily, Athanasios Alexiou, Marios Papadakis, Gaber El-Saber Batiha   +5 more
wiley   +1 more source

Pharmacokinetic Prediction and Cytotoxicity of New Quercetin Derivatives

Chemistry &Biodiversity, EarlyView.
ABSTRACT Quercetin (QUE) possesses various pharmacological properties; however, its low bioavailability and solubility hinder its beneficial effects. Enzymatic glycosylation has been explored to improve these aspects. In the present study, we used a sucrose phosphorylase variant to catalyze the regioselective transglucosylation of QUE, predicted the ...
Michele Goulart dos Santos, Marie Demonceaux, Lucia Emanueli Schimith, Marine Goux, Claude Solleux, Ana Luiza Muccillo‐Baisch, Bruno Dutra Arbo, Corinne Andre‐Miral, Mariana Appel Hort   +8 more
wiley   +1 more source

Modified titration of donanemab reduces ARIA risk and maintains amyloid reduction. [PDF]

Alzheimers Dement
Wang H, Serap Monkul Nery E, Ardayfio P, Khanna R, Otero Svaldi D, Gueorguieva I, Shcherbinin S, Andersen SW, Hauck PM, Engle SE, Brooks DA, Collins EC, Fox NC, Greenberg SM, Salloway S, Mintun MA, Sims JR.   +16 more
europepmc   +1 more source

Comparison of Pittsburgh compound B and florbetapir in cross-sectional and longitudinal studies [PDF]

, 2019
Bateman, Randall J, Benzinger, Tammie L.S., et al,, Flores, Shaney, Gordon, Brian A, Hornbeck, Russ C, Joseph-Mathurin, Nelly, McDade, Eric, Morris, John C, Snider, Barbara J, Speidel, Benjamin, Vlassenko, Andrei G, Wang, Guoqiao, Xiong, Chengjie   +13 more
core   +1 more source

Ethnomedicinal uses, phytochemistry, pharmacological activities, and toxicology of the subfamily Gomphrenoideae (Amaranthaceae): A comprehensive review

Chemistry &Biodiversity, Accepted Article.
The subfamily Gomphrenoideae is composed of about 480 accepted species, many of which have been historically used as medicinal plants, reason why they have been studied in terms of chemical profile, biological activity, and safety. This review consolidates the advances in research on this subfamily over the past 47 years, emphasizing its promising ...
Dayanna Isabel Araque Gelves, Giulia Cristina Andreoli de Souza, Alvaro Jose Hernandez Tasco, Marcos Jose Salvador   +3 more
wiley   +1 more source

Clinical Performance of LucentAD Complete: A Multi-Analyte Algorithmic Blood Test for Detecting Brain Amyloid with a Scalable, Multiplexed Digital Immunoassay

Wilson D, Copeland K, Vasko A, Hesterberg L, Khare M, Wolfe M, Sheehy P, Verberk IM, Miller M, Teunissen CE.   +9 more
europepmc   +1 more source

Japanese participant data from three gantenerumab trials in early Alzheimer's disease. [PDF]

Alzheimers Dement
Asada T, Thanasopoulou A, Delmar P, Wojtowicz J, Smith J, Yoshiyama Y, Yokoi K, Watanabe C, Isozaki M, Ozaki R, Ishida T, Tatsuda H, Tamaoka A.   +12 more
europepmc   +1 more source

The BIN1 rs744373 SNP is associated with increased tau-PET levels and impaired memory [PDF]

, 2019
Ances, Beau, Cairns, Nigel J., Carroll, Maria, Ewers, M, Franzmeier, N, Holtzman, David, Householder, Erin, Leon, Sue, Mintun, Mark A., Morris, John, Neitzel, J, Oliver, Angela, Raichle, Marcus, Rubinski, A, Schneider, Stacy, Taylor-Reinwald, Lisa   +15 more
core   +1 more source