Results 321 to 330 of about 516,976 (376)

Differences in Alzheimer's disease blood biomarker stability: Implications for the use of tau/amyloid ratios. [PDF]

Alzheimers Dement
Figdore DJ, Schuder BJ, Ashrafzadeh-Kian S, Gronquist T, Bornhorst JA, Algeciras-Schimnich A.   +5 more
europepmc   +1 more source

Descemet's Membrane Detachment During Cataract Surgery in Lattice Corneal Dystrophy Type I: Histopathological Analysis of Posterior Corneal Involvement. [PDF]

Cureus
Matsumoto A, Fukuoka H, Sotozono C.
europepmc   +1 more source

SAAP‐148 Oligomerizes into a Hexamer Forming a Hydrophobic Inner Core

ChemBioChem, EarlyView.
The highly cationic and hydrophobic antimicrobial peptide SAP‐148 effectively eradicates multidrug‐resistant bacteria, persistent cells, and biofilms without inducing resistance. Its efficiency is likely due to its ability to disrupt bacterial membranes as an oligomer, forming a stable alpha‐helical hexameric bundle with three parallel dimers that ...
Aden Hodzic, Djenana Vejzovic, Altea Topciu, Kirill Kuhlmann, Raj Kumar, Maria Andrea Mroginski, Alejandra de Miguel, Pia Hofmann, Klaus Zangger, Markus Weingarth, Robert A. Cordfunke, Jan W. Drijfhout, Peter Nibbering, Michal Belicka, Karl Lohner, Nermina Malanovic   +15 more
wiley   +1 more source

Long-term follow-up of retinal amyloid angiopathy in a large Chinese family with hereditary amyloid transthyretin. [PDF]

BMC Ophthalmol
Xu J, Shu N, Liu X, Gu P, Wang Y, Li S.
europepmc   +1 more source

Translational Medicine in Alzheimer's Disease: The Journey of Donanemab From Discovery to Clinical Application

Chronic Diseases and Translational Medicine, EarlyView.
Donanemab, approved by the U.S. FDA in July 2024, targets amyloid plaques in the brain to treat Alzheimer's disease in patients with mild cognitive impairment or mild dementia. ABSTRACT Substantial research has been conducted to identify an efficient treatment for Alzheimer's disease (AD).
Nandhini Jayaprakash, Karthikeyan Elumalai   +1 more
wiley   +1 more source

Early involvement of D-serine in β-amyloid-dependent pathophysiology. [PDF]

Cell Mol Life Sci
Billard JM, Ploux E, Largilliere S, Corvaisier S, Gorisse-Hussonnois L, Radzishevsky I, Wolosker H, Freret T.   +7 more
europepmc   +1 more source

Early presentation of spastic paraparesis in individuals carrying PSEN1 mutations: a clinical and genetic analysis. [PDF]

Alzheimers Res Ther
Jih KY, Hsu TR, Fuh JL, Lee TH, Lin YS, Fang SY, Liao YC, Lee YC.   +7 more
europepmc   +1 more source

Role of Tag Team Rounds in Accurate Diagnosis and Management of Cardiac Amyloidosis. [PDF]

JACC Case Rep
Wahaj A, Maqsood N, Hassler JR, Patil PV, Fabrizio CA.   +4 more
europepmc   +1 more source

Statement of Retraction: Sulforaphane ameliorates amyloid-β-induced inflammatory injury by suppressing the PARP1/SIRT1 pathway in retinal pigment epithelial cells. [PDF]

Bioengineered
europepmc   +1 more source

Elevated serum cortisol associated with early-detected increase of brain amyloid deposition in Alzheimer's disease imaging biomarkers among menopausal women: The Framingham Heart Study. [PDF]

Alzheimers Dement
Salardini A, Himali JJ, Abdullah MS, Chaudhari R, Young V, Zilli EM, McGrath ER, Gonzales MM, Thibault EG, Salinas J, Aparicio HJ, Himali D, Ghosh S, Buckley RF, Satizabal CL, Johnson KA, DeCarli C, Fakhri GE, Vasan RS, Beiser AS, Seshadri S.   +20 more
europepmc   +1 more source