Results 51 to 60 of about 183,744 (183)
UFMylation of NLRP3 Prevents Its Autophagic Degradation and Facilitates Inflammasome Activation
This article studies the role of UFMylation in NLRP3 inflammasome activation. It reveals that UFMylation, mediated by the E3 Ufm1‐ligase 1 (Ufl1), maintains NLRP3 stability by preventing its ubiquitination and subsequent autophagic degradation.
Jiongjie Jing+14 more
wiley +1 more source
Abstract Book for the 27th Congress of the European Hematology Association
HemaSphere, Volume 6, Issue S3, Page 1-4130, June 2022.
wiley +1 more source
Background: Hereditary transthyretin amyloid (ATTRv) is a systemic amyloidosis with mainly neurological and cardiac symptoms. The aim of this study was to evaluate the outcome of [18F]Flutemetamol PET/CT-scan of the heart in long-term survivors with ...
Sofia Möckelind+5 more
semanticscholar +1 more source
ABSTRACT Community‐acquired respiratory viral infections (CARV) significantly impact patients with hematological malignancies (HM), leading to high morbidity and mortality. However, large‐scale, real‐world data on CARV in these patients is limited. This study analyzed data from the EPICOVIDEHA‐EPIFLUEHA registry, focusing on patients with HM diagnosed ...
Jon Salmanton‐García+99 more
wiley +1 more source
Fungal Biomolecules for Food and Pharmaceutical Application
The review summarizes the diverse roles of fungal biomolecules in the food and pharmaceutical industries and highlights their significant contribution to modern medicine and health‐related fields. ABSTRACT Mushrooms have long been an integral part of human culture and health and are valued for their nutritional and therapeutic properties.
Giancarlo Angeles Flores+4 more
wiley +1 more source
Trem2 acts as a non‐classical receptor of interleukin‐4 to promote diabetic wound healing
This study elucidates the pivotal role of TREM2 in diabetic wound healing. This study identified the key regulatory gene involved in diabetic wound healing as TREM2. This study has found that IL‐4 functions as an upstream ligand, activating TREM2. This study provides Evidence of the regulatory effects of macrophages by IL‐4/TREM2/AP‐1/LIF pathway on ...
Xinlin Zhu+11 more
wiley +1 more source
2021 ACVIM Forum Research Abstract Program
Journal of Veterinary Internal Medicine, Volume 35, Issue 6, Page 2943-3079, November/December 2021.
wiley +1 more source
Inotersen therapy of transthyretin amyloid cardiomyopathy
Background: Cardiomyopathy is a major cause of death in patients with systemic transthyretin amyloidosis. Long term effect of therapy designed to inhibit hepatic production of the amyloid precursor has not been established in cardiomyopathy.
N. Dasgupta+4 more
semanticscholar +1 more source
EHA2021 Virtual Congress Abstract Book
HemaSphere, Volume 5, Issue S2, June 2021.
wiley +1 more source
Resurrection and emendation of the Hypoxylaceae, recognised from a multigene phylogeny of the Xylariales [PDF]
A multigene phylogeny was constructed, including a significant number of representative species of the main lineages in the Xylariaceae and four DNA loci the internal transcribed spacer region (ITS), the large subunit (LSU) of the nuclear rDNA, the ...
Heitkämper, Simone+10 more
core +2 more sources