Results 361 to 370 of about 181,705 (382)
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Journal of the American Podiatric Medical Association, 1990
The authors present a review of amyloidosis and its classification and clinical presentations. They also discuss its diagnosis and treatment, and present a case of amyloid deposition in the plantar weightbearing aspects of the feet, which exemplifies the classic clinical findings.
P K, Geistler, K G, Canter, N A, Staley
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The authors present a review of amyloidosis and its classification and clinical presentations. They also discuss its diagnosis and treatment, and present a case of amyloid deposition in the plantar weightbearing aspects of the feet, which exemplifies the classic clinical findings.
P K, Geistler, K G, Canter, N A, Staley
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Histopathology, 1994
Amyloidosis is a heterogeneous group of disorders characterized by extracellular deposition of abnormal protein fibrils which are dérived from different proteins in different forms of the disease. Asymptomatic amyloid deposition in a variety of tissues is a universal accompaniment of ageing, and clinical amyloidosis is not rare.
S Y, Tan, M B, Pepys
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Amyloidosis is a heterogeneous group of disorders characterized by extracellular deposition of abnormal protein fibrils which are dérived from different proteins in different forms of the disease. Asymptomatic amyloid deposition in a variety of tissues is a universal accompaniment of ageing, and clinical amyloidosis is not rare.
S Y, Tan, M B, Pepys
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Journal of Inherited Metabolic Disease, 2015
AbstractAlkaptonuria (AKU) is an ultra‐rare inborn error of metabolism developed from the lack of homogentisic acid oxidase activity, causing homogentisic acid (HGA) accumulation that produces an HGA‐melanin ochronotic pigment, of hitherto unknown composition. Besides the accumulation of HGA, the potential role and presence of unidentified proteins has
MILLUCCI, LIA +6 more
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AbstractAlkaptonuria (AKU) is an ultra‐rare inborn error of metabolism developed from the lack of homogentisic acid oxidase activity, causing homogentisic acid (HGA) accumulation that produces an HGA‐melanin ochronotic pigment, of hitherto unknown composition. Besides the accumulation of HGA, the potential role and presence of unidentified proteins has
MILLUCCI, LIA +6 more
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Serum amyloidosis: a cardiac amyloidosis
European Heart Journal - Cardiovascular Imaging, 2023Jeremy A Slivnick +3 more
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Transplantation for amyloidosis
Current Opinion in Oncology, 2007High-dose chemotherapy increasingly is being used for the management of patients with immunoglobulin light-chain amyloidosis. We describe nearly 300 patients who had treatment combining high-dose chemotherapy and stem cell transplantation at Mayo Clinic and review the recent literature.We review outcomes, engraftment data, and predictors of early ...
Shaji Kumar +4 more
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Current Opinion in Rheumatology, 1993
Major advances of the past year in the amyloidoses include a better understanding of the polymorphism of the acute-phase reactant serum amyloid A protein and the appearance of a new mouse model for primary amyloidosis. The list of single point mutations in transthyretin in different families with slightly varied clinical manifestations of the disease ...
Alan S. Cohen, Lee Anna Jones
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Major advances of the past year in the amyloidoses include a better understanding of the polymorphism of the acute-phase reactant serum amyloid A protein and the appearance of a new mouse model for primary amyloidosis. The list of single point mutations in transthyretin in different families with slightly varied clinical manifestations of the disease ...
Alan S. Cohen, Lee Anna Jones
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RNA-targeting and gene editing therapies for transthyretin amyloidosis
Nature Reviews Cardiology, 2022Alberto Aimo +9 more
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Fortschritte der Medizin, 1976
Recent studies have clearly indicated that amyloid is a generic term which includes a number of different substances, all of which have a beta-pleated sheet structure and a characteristic fibrillar appearance in the electron microscope. The most common types are made of immunoglobulin light chain (AL) fragments in the primary and myeloma-associated ...
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Recent studies have clearly indicated that amyloid is a generic term which includes a number of different substances, all of which have a beta-pleated sheet structure and a characteristic fibrillar appearance in the electron microscope. The most common types are made of immunoglobulin light chain (AL) fragments in the primary and myeloma-associated ...
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Journal of the American Academy of Dermatology, 1988
Cutaneous lesions are present in up to 40% of patients with primary and myeloma-associated systemic amyloidosis and occur as a result of tissue deposition of immunoglobulin light chain material derived from a circulating paraprotein. The occurrence of waxy, purpuric mucocutaneous lesions provides a crucial early pointer to underlying occult plasma cell
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Cutaneous lesions are present in up to 40% of patients with primary and myeloma-associated systemic amyloidosis and occur as a result of tissue deposition of immunoglobulin light chain material derived from a circulating paraprotein. The occurrence of waxy, purpuric mucocutaneous lesions provides a crucial early pointer to underlying occult plasma cell
openaire +3 more sources