Results 41 to 50 of about 555,786 (138)

PESQUISA DE CAMPYLOBACTER SPP. EM CARNES DE FRANGO COMERCIALIZADAS NA CIDADE DE CAMPO MOURÃO-PR

Alimentos e Nutrição, 2012
A campilobacteriose causa um grande impacto na saúde pública em todo o mundo, sendo em muitos pa- íses a causa mais frequente de gastroenterite em humanos causada por alimentos.
Karina de Oliveira GONÇALVES, Elisa Hizuru Uemura YAMANAKA, Aline Paula Isolani ALMEIDA, Luciano de Jesus CHANO, Alessandra Braga RIBEIRO   +4 more
doaj  

Cytotoxic and pro-apoptotic action of MjTX-I, a phospholipase A2 isolated from Bothrops moojeni snake venom, towards leukemic cells

Journal of Venomous Animals and Toxins including Tropical Diseases, 2018
Background Chronic myeloid leukemia (CML) is a BCR-ABL1 + myeloproliferative neoplasm marked by increased myeloproliferation and presence of leukemic cells resistant to apoptosis.
Rogério Bodini Benati, Tássia Rafaela Costa, Maira da Costa Cacemiro, Suely Vilela Sampaio, Fabíola Attié de Castro, Sandra Mara Burin   +5 more
doaj   +1 more source

Envolvimento público no Registro Brasileiro de Paralisia Cerebral: um estudo exploratório, sequencial, de métodos mistos

Developmental Medicine &Child Neurology, EarlyView.
Resumo Objetivo Descrever a implementação da estratégia de envolvimento do público baseada nas normas do Reino Unido para o envolvimento do público em pesquisa no Registro Brasileiro de Paralisia Cerebral (RB‐PC). Métodos Realizamos um estudo participativo, exploratório, sequencial, de métodos mistos.
Luana Cristina da Silva, Claire Kerr, Israt Jahan, Raphael Fagundes Figueira Pinho, Aline Lincoln Silveira, Nádia Badawi, Gulam Khandaker, Gabriela Lorençoni Pauletti, Egmar Longo, Mercedes Ruiz Brunner, Paula Silva de Carvalho Chagas, Hércules Ribeiro Leite   +11 more
wiley   +1 more source

Frequência escolar em indivíduos com paralisia cerebral no Brasil

Developmental Medicine &Child Neurology, Volume 68, Issue 12, Page e219-e229, December 2026.
Objetivo Identificar fatores associados à frequência escolar entre crianças, adolescentes e jovens adultos brasileiros com paralisia cerebral (PC), utilizando dados populacionais do Registro Brasileiro de Paralisia Cerebral (RBPC). Método Este estudo transversal analisou dados de 774 indivíduos com PC, com idades entre 4 e 21 anos, registrados no RPBC.
Ricardo Rodrigues de Sousa Junior, Luana Cristina da Silva, Ana Cristina Resende Camargos, Eliane Beatriz Cunha Policiano, Lívia Ferreira Coutinho Alonso, Nadia Badawi, Israt Jahan, Gulam Khandaker, Maria De Las Mercedes Ruiz Brunner, Paula Silva de Carvalho Chagas, Hércules Ribeiro Leite   +10 more
wiley   +1 more source

Simultaneous Infection With Genetically Distinct Trypanosoma cruzi Isolates Is Associated With Distinct Myocardial Innate Immune Transcriptional Profiles During Acute Infection in Mice

Parasite Immunology, Volume 48, Issue 10, October 2026.
ABSTRACT Innate immune receptors are central to host resistance against Trypanosoma cruzi infection, yet how parasite genetic diversity is associated with these responses remains poorly understood. Here, we characterized acute infection outcomes and myocardial innate immune transcriptional profiles in mice subjected to single and mixed infections with ...
George Harisson Felinto Sampaio, Andressa Noronha Barbosa‐Silva, Carlos Ramon do Nascimento Brito, Lucas Abrantes Batista, Christiane Carlos Araújo de Negreiros, Ramayana Morais de Medeiros Brito, Rand Randall Martins, Manuela Sales Lima Nascimento, Antonia Claudia Jácome da Câmara, Paulo Marcos da Matta Guedes, Lúcia Maria da Cunha Galvão   +10 more
wiley   +1 more source

AVALIAÇÃO DO CUSTO DE REPETIÇÕES DE EXAMES DE CLASSIFICAÇÕES SANGUÍNEAS EM UM HOSPITAL UNIVERSITÁRIO

Hematology, Transfusion and Cell Therapy
Introdução: Nos processos de determinações laboratoriais as interferências pré-analíticas são as mais frequentes. Dentre os fatores que a etapa pré-analítica pode interferir está a solicitação de exames desnecessários ou repetidos, causando aumento da ...
RHT Vasconcelos, IB Silva, CA Alves, HRS Brito, JUV Lacerda, NAC Tavares   +5 more
doaj   +1 more source

Lack of association between methylenetetrahydrofolate reductase C677T polymorphism, HPV infection and cervical intraepithelial neoplasia in Brazilian women

BMC Medical Genetics, 2019
Background Cervical cancer has high prevalence and mortality rates in worldwide female population. Persistent infection by high-risk Human Papillomavirus (hr-HPV) is the main cause of this cancer.
Nayara Nascimento Toledo Silva, Adriano de Paula Sabino, Alexandre Tafuri, Angélica Alves Lima   +3 more
doaj   +1 more source

Underexplored Ligand‐Binding Features of FabI From Staphylococcus aureus and Escherichia coli: A Comparative Pharmacophoric Modeling and Surface Mapping Approach

ChemMedChem, Volume 21, Issue 15, 14 August 2026.
Antimicrobial resistance highlights the urgent need for novel FabI inhibitors. Using an integrated computational approach combining ConPhar pharmacophore modeling, FTMap surface mapping, and PLIP interaction profiling across experimental structures and structures from MD simulations, we identified a conserved binding core (Y156/Y157, A95) and ...
Pedro Tenório T. F. Leite, Lucas H. S. Ocarino, Gabriel C. Veríssimo, Philipe O. Fernandes, Dara Fernanda Pereira, Fernanda Kelly M. e Oliveira, Alberto Marbán‐González, José L. Medina‐Franco, Mateus Sá M. Serafim, Thales Kronenberger, Vinícius G. Maltarollo   +10 more
wiley   +1 more source

Long COVID with Symptoms Persisting for More than Six Months in Unvaccinated Patients: Investigation of Biochemical Changes Associated with Chronic Manifestations

COVID
Long COVID is a complex condition characterized by persistent symptoms following SARS-CoV-2 infection. Understanding its biochemical mechanisms is essential for effective management and treatment strategies. Objective: This study investigated biochemical
Matheus Torres, Giulia Davanço, Isabela de Paula Destro, Neif Murad, Glaucia Luciano da Veiga, Pedro Henrique Alves Reis, Renata de Lion Botero Martins, Beatriz da Costa Aguiar Alves, Rodrigo Daminello Raimundo, Juliana Zangirolami-Raimundo, Fernando Luiz Affonso Fonseca   +10 more
doaj   +1 more source

Estrogen Receptor Beta Activation Coordinates Liver Lipid Remodeling and Metabolic Fluxes, Preventing Lipotoxicity

Comprehensive Physiology, Volume 16, Issue 4, August 2026.
ERβ activation restores glucose and lipid homeostasis by remodeling the hepatic lipidome. Mechanistically, it promotes complete fatty acid oxidation and decreases Acetyl‐CoA levels, leading to reduced ketogenesis and lipotoxicity, as demonstrated through in vivo and in vitro approaches.
Debora Santos Rocha, Eloisa Vilas‐Boas, Camille C. Caldeira da Silva, Everton L. Vogt, Marcos Yoshinaga, Mariana Pacheco Teixeira de Carvalho, Maiara I. C. Queiroz, Tiago Eugênio Oliveira da Silva, Sayuri Miyamoto, Alicia J. Kowaltowski   +9 more
wiley   +1 more source