Results 111 to 120 of about 116,100 (235)

Longitudinal untargeted metabolomics of cognitive impairment in Parkinson's disease

Alzheimer's &Dementia, Volume 22, Issue 10, October 2026.
Abstract INTRODUCTION Cognitive impairment is a common non‐motor symptom of Parkinson's disease (PD), yet the mechanism remains unclear. METHODS Longitudinal serum samples from PD patients in a community‐based case–control study were profiled, with cognition assessed by the Mini‐Mental State Examination at baseline and follow‐up.
Yuyuan Lin, Yu Yu, Keren Zhang, Irish Del Rosario, Aline Duarte Folle, Elizabeth Rose Mayeda, Dean P. Jones, Douglas I. Walker, Jeff Bronstein, Adrienne M. Keener, Kimberly C. Paul, Beate Ritz   +11 more
wiley   +1 more source

Investigation Into the Metabolism and Elimination Behavior of RU 58841, and Its Influence on the Steroid Profile in Humans

Biomedical Chromatography, Volume 40, Issue 10, October 2026.
ABSTRACT RU 58841 is a nonsteroidal antiandrogen, developed for the treatment of androgen‐dependent conditions. This study aimed to characterize the human metabolism of RU 58841 for the first time and to assess its systemic exposure following topical administration.
Aylin Okutan, Oliver Krug, Gregor Fußhöller, Thomas Piper, Mario Thevis   +4 more
wiley   +1 more source

Quantification of the Carboxylated LGD‐4033 Long‐Term Metabolite in Human Micro‐Dose Excretion Study Urine Samples

Drug Testing and Analysis, Volume 18, Issue 10, Page 1321-1327, October 2026.
A validated LC‐HRMS/MS method enabled the first quantitative determination of the LGD‐4033 long‐term metabolite (M5‐b) in urine following controlled micro‐dose administration. The generated urinary reference data support the interpretation of adverse analytical findings and anti‐doping result management. ABSTRACT Selective androgen receptor modulators (
Panagiotis Sakellariou, Sebastian Marcel Schröder, Jasmin Thelen, Linus Korsmeier, Sven Guddat, Christian Görgens, Andreas Thomas, Mario Thevis   +7 more
wiley   +1 more source

Plant Part–Specific Differences in Ashwagandha (Withania somnifera): A Comparative Evaluation of Root and Leaf Evidence for Safety and Regulation

Food Science &Nutrition, Volume 14, Issue 10, October 2026.
This review contrasts the root and leaf of Withania somnifera (ashwagandha) across phytochemistry, clinical evidence, and regulatory context. Root preparations are dominated by withanolide A, D, and glyco‐withanolides, with multiple randomized controlled trials supporting reductions in stress, anxiety, and insomnia alongside a favorable safety profile.
Abhijit Dutta, Jang Bahadur Gupta
wiley   +1 more source

Effects of Anabolic Steroids: Morris Foundation Study [PDF]

, 1981
Anabolic steroids, a drug commonly given to promote growth, especially in race or show horses, may be harmful to a mare's reproductive performance, a veterinary scientist says.

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Studying the effect of anabolic androgenic steroids on the oral health of athletes

Journal of Craniomaxillofacial Research, 2017
Introduction: Anabolic androgenic steroids (AAS) are the synthetic derivatives of testosterone hormone; which are used by athletes; in order to increase muscle size, improve physical image and increase strength. They are usually being used out of medical
Arghavan Tonkaboni, Hamed Zare, Mohammad Javad Kharrazi Fard   +2 more
doaj  

Fibro‐Adipogenic Progenitor Ablation Triggers Muscle Atrophy Through Cell Death‐Induced Inflammation

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 5, October 2026.
ABSTRACT Background Skeletal muscle mass maintenance involves coordination of myofibers with mononuclear cell populations, including satellite cells, resident macrophages and fibro‐adipogenic progenitors (FAPs). FAPs, identified by surface expression of PDGFRα, are important contributors to muscle homeostasis, as genetic ablation of FAPs induces rapid ...
Yangyi E. Luo, Young il Lee, Zoe Abe‐Teh, Rachel Y. Young, Lan Wei‐LaPierre, Elisabeth R. Barton   +5 more
wiley   +1 more source

The Effect of Carbetocin on Cardiac Repolarization: A Randomized, Placebo‐ and Positive‐Controlled QT/QTc Study in Healthy Adults

Clinical and Translational Science, Volume 19, Issue 10, October 2026.
ABSTRACT Carbetocin is an oxytocin receptor agonist used for postpartum hemorrhage prevention. While oxytocin is known to transiently prolong the QT/QTc interval, robust QTc data for carbetocin are limited. Carbetocin is known to elevate HR, which can impact QTc analyses; thus, a dose that did not overly elevate HR was important to select.
Daniël M. Jonker, Katie Barletta, Ekaterine Bagci, Kyle Raymond, Philippe Pinton   +4 more
wiley   +1 more source

Anabolic Steroids Revolutionizing The Sport of Bodybuilding

, 2016
iv, 31 p.The sport of bodybuilding is growing each and every year with increasing competition as well as popularity. Beginning with Eugen Sandow, the father of bodybuilding, in 1891 the sport has drastically changed from ‘the big show’ to the modern Mr ...
Eckenrod, Matthew
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Microbial Biotransformation of Some Anabolic Steroids

, 2022
Microbial biotransformations of various anabolic steroids are reviewed. Studies on oxidation, reduction, and carbon bond cleavage are highlighted.
Choudhary, M. Iqbal, Abu-Darwish, Mohammad S., M. Haniffa, Haroon, Mohammad, Mohammad Yasin, Al-Hiari, Yusuf, Habash, Maha, Al-Najdawi, Manal   +6 more
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