Results 41 to 50 of about 206,353 (256)

Incidence and predictors of recovery from anaemia within an HIV-infected South African Cohort, 2004-2010

The Pan African Medical Journal, 2014
INTRODUCTION: Anaemia is one of the most frequent haematological complications in HIV-infected persons. Understandingfactors associated with recovery from anaemia during ART is vital in improving clinical outcomes since anaemia is a strong predictor of ...
Zibusiso Ndlovu, Tobias Chirwa, Simbarashe Takuva   +2 more
doaj   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

Bacteraemia in Kenyan children with sickle-cell anaemia: a retrospective cohort and case-control study. [PDF]

, 2009
BACKGROUND: In sub-Saharan Africa, more than 90% of children with sickle-cell anaemia die before the diagnosis can be made. The causes of death are poorly documented, but bacterial sepsis is probably important.
Uyoga, Sophie, Berkley, James, Macharia, Alex, McAuley, Charlotte F, Opi, DH, Kevin Marsh, J Anthony G Scott, Mwarumba, Salim, Berkley, James A, Ndila, C, Scott, John, Carolyne Ndila, Berkley, JA, Thomas N Williams, Sophie Uyoga, Williams, TN, Makani, J, James A Berkley, Sharif, SK, McAuley, CF, Daniel H Opi, Mwarumba, S, Uyoga, S, Macharia, A, Albert Komba, Marsh, K, Scott, JA, Charlotte F McAuley, Sharif, Shahnaaz K, Scott, J Anthony G, Williams, Thomas N, Julie Makani, Ndiritu, Moses N, Salim Mwarumba, Moses N Ndiritu, Komba, Albert, Williams, Thomas, Komba, A, Opi, Daniel H, Makani, Julie, Marsh, Kevin, Ndiritu, MN, Alex Macharia, Shahnaaz K Sharif, Ndila, Carolyne   +44 more
core   +1 more source

Association of Anaemia with Metastasis in Non Haematological Malignancies: A Cross-sectional Study [PDF]

Journal of Clinical and Diagnostic Research
Introduction: Anaemia and cancer are two non communicable diseases with high global prevalence. The presence of anaemia in cancer patients is common, and its aetiology is multifactorial. Aim: To analyse the clinical profile, type and severity of anaemia
Bhumika Vaishnav, Nirali Thakkar, Aniruddh N Wadivkar, Saish Mondkar, Kshiti   +4 more
doaj   +1 more source

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito, Ryuichi Yoshimura, Takaki Yamauchi, Yuta Funakoshi, Hirotaka Sonoda, Seiji Kobayashi, Hiroyuki Terawaki, Takafumi Ito   +7 more
wiley   +1 more source

The health of pregnant women in rural Tanzania with specific emphasis on anaemia and the impact of socially marketed insecticide treated bednets [PDF]

, 2002
Anaemia in pregnancy is one of the main maternal health problems globally, affecting over 50% of pregnant women in sub-Saharan Africa. Although not always shown to have a causal link, severe anaemia contributes to maternal morbidity and mortality and ...
Marchant, Tanya Jayne
core   +1 more source

Baseline severe anaemia should not preclude use of zidovudine in antiretroviral‐eligible patients in resource‐limited settings

Journal of the International AIDS Society, 2010
Background Stavudine is no longer recommended as part of first‐line therapy for patients initiating antiretroviral therapy (ART) in Uganda. Most patients are currently initiated on zidovudine‐containing regimens, which can induce anaemia. We investigated
Agnes N Kiragga, Barbara Castelnuovo, Damalie Nakanjako, Yukari C Manabe   +3 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Seasonal intermittent preventive treatment for the prevention of anaemia and malaria in Ghanaian children: a randomized, placebo controlled trial. [PDF]

, 2008
BACKGROUND: Malaria and anaemia are the leading causes of morbidity and mortality in children in sub-Saharan Africa. We have investigated the effect of intermittent preventive treatment with sulphadoxine-pyrimethamine or artesunate plus amodiaquine on ...
Kweku Margaret, Liu Dongmei, Adjuik, Martin, Daniel Chandramohan, Greenwood Brian, Margaret Kweku, Binka Fred, Fred Binka, Binka, Fred, Chandramohan, Daniel, Mahmood Seidu, Liu, Dongmei, Dongmei Liu, Seidu, Mahmood, Martin Adjuik, Greenwood, Brian, Brian Greenwood, Kweku, Margaret, Seidu Mahmood, Adjuik Martin, Chandramohan Daniel   +20 more
core   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source