Results 71 to 80 of about 166,404,517 (251)

Study of some Pathological Aspects in Sheep Infected with Fasciola gigantica

The Iraqi Journal of Veterinary Medicine, 1986
Little information is available on the pathophysiological changes caused by Fasciola gigantica. The present study aimed at the ellucidation of these changes in Awasi lambs infected with various doses (100, 300 and 600) of metacercariae.
F. M.Wahid, K. I.Altaif, S. R.Ali
doaj   +1 more source

Management of Anaemia of Chronic Disease: Beyond Iron-Only Supplementation. [PDF]

Nutrients, 2021
Pasini E, Corsetti G, Romano C, Aquilani R, Scarabelli T, Chen-Scarabelli C, Dioguardi FS.   +6 more
europepmc   +1 more source

TH/TRs–COL11A2 Axis Mediates Loss of a Differentiated Astrocyte State in Hypogyrified Brains

Advanced Science, EarlyView.
Using a gyrencephalic congenital hypothyroidism pig model, this study reveals cerebral atrophy and cortical hypogyrification. Single‐cell sequencing identifies astrocytes as major TH‐responsive cells, with the COL11A2‐enriched Astro‐2 state nearly absent.
Ying Zhang, Xiao Wang, Hongyan Ma, Pengcheng Lyu, Shuangjie Tian, Ruojun Zong, Jiani Chen, Gang Ren, Yongjiang Yang, Zichen Yang, Guosong Qin, Naishi Li, Yanfang Wang, Jianwei Jiao, Jianguo Zhao   +14 more
wiley   +1 more source

Radical Resection of the Third Portion of the Duodenum for Secondary Aortoduodenal Fistula

Annals of Gastroenterological Surgery, EarlyView.
Secondary aortoduodenal fistula most commonly involves the third portion of the duodenum and requires definitive management of both vascular and gastrointestinal components. We demonstrate a step‐by‐step technique for radical duodenal resection and reconstruction performed in structured collaboration with cardiovascular surgeons.
Koji Kubota, Akira Shimizu, Tsuyoshi Notake, Tatsuichiro Seto, Yuji Soejima   +4 more
wiley   +1 more source

The Endocrine Giants of Chronic Kidney Disease

Journal of the Pakistan Medical Association
Chronic Kidney Disease (CKD) is increasingly being recognized as an endo-metabolic disorder in which a cascade of hormonal and electrolyte imbalances impacts the morbidity and mortality.
Sourabh Sharma, Neha Sharma, Sanjay Kalra   +2 more
doaj   +1 more source

Long‐Term Stoma‐Free Outcomes After Diverting Stoma Closure Following Radiation‐Based Neoadjuvant Treatment for Rectal Cancer

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Aim Long‐term stoma‐free outcomes after diverting stoma closure in patients who underwent sphincter‐preserving rectal cancer surgery with double‐stapling technique (DST) reconstruction following radiation‐based neoadjuvant treatment remain unclear.
Hidetaka Ichikawa, Shimpei Matsui, Kentaro Sato, Tatsuki Noguchi, Takashi Sakamoto, Toshiki Mukai, Tomohiro Yamaguchi, Takashi Akiyoshi   +7 more
wiley   +1 more source

Prohepcidin Levels in Refractory Anaemia Caused by Lead Poisoning

Case Reports in Gastroenterology, 2008
Recent research evidence suggests a central role for hepcidin in iron homeostasis. Hepcidin is a hormone synthesized in the liver. Hepcidin is also thought to play a vital role in the pathogenic mechanism of anaemia in patients with inflammation or ...
Jayantha Arnold, Mark Busbridge, Arvind Sangwaiya, Bharati Bhatkal, Parth Paskaran, Arabinda Pal, Frank Geoghegan, Terence Kealey   +7 more
doaj   +1 more source

HOPE Kids 2: Phase 3, Randomized Trial of Voxelotor in Children With SCD and Conditional Cerebral Blood Flow Velocities

American Journal of Hematology, EarlyView.
ABSTRACT Children with SCD have elevated stroke risk, correlated with cerebral blood flow velocity (CBFV). HOPE Kids 2 was a phase 3, multicenter, double‐blind, placebo‐controlled trial evaluating the effect of voxelotor on CBFV. Participants aged 2 to < 15 years with SCD (HbSS/HbSβ0) and conditional CBFV (170 to < 200 cm/s) were randomized 1:1 to ...
Halima Bello‐Manga, Shehu Umar Abdullahi, Hoda Hassab, Biobele Brown, Videlis Nduba, Jessie Githanga, Adeseye Michael Akinsete, Amal El‐Beshlawy, Diana Hanna, Catherine Segbefia, Iheanyi Okpala, Azza Tantawy, Bernhards Ogutu, Venée N. Tubman, Vivian Paintsil, Yasser Wali, Mohammed Essa, Paul Telfer, Sandy Dixon, Anne Hickman, Jennifer F. Doss, Mark W. Davis, Jeremy Rupon, Fenella J. Kirkham, R. Clark Brown, on behalf of the HOPE Kids 2 Investigators, Amal El‐Beshlawy, Mohamed Badr, Diana Hanna*, Hoda Hassab, Azza Tantawy, Vivian Paintsil, Catherine Segbefia, Raffaella Colombatti, Daniela Cuzzubbo, Silverio Perrotta, Jessie Githanga, Videlis Nduba, Bernhards Ogutu, Shehu Umar Abdullahi, Adeseye Michael Akinsete, Halima Bello‐Manga, Biobele Brown, Iheanyi Okpala, Yasser Wali, Mohammed Essa, Banu Kaya, Paul Telfer, Ofelia Alvarez, Natasha Archer, Shayla Bergmann, R Clark Brown, Andrew Campbell, Carlton Dampier*, Richard Hurwitz, Erin Jackson, Janet Kwiatkowski, Melissa M. McNaull*, Venée N. Tubman   +58 more
wiley   +1 more source

Associations between mild-to-moderate anaemia in pregnancy and helminth, malaria and HIV infection in Entebbe, Uganda. [PDF]

, 2007
It is suggested that helminths, particularly hookworm and schistosomiasis, may be important causes of anaemia in pregnancy. We assessed the associations between mild-to-moderate anaemia (haemoglobin >8.0 g/dl and
Nabulime, Juliet, Patrick Woodburn, Omoding, Nicholas, Kizito, D, Morison, LA, Muhangi, Lawrence, Lawrence Muhangi, Alison M. Elliott, Mildred Omara, Juliet Nabulime, Elliott, Alison M, Kizito, Dennison, Elliott, AM, Nicholas Omoding, Nabulime, J, Mpairwe, Harriet, Ameke, C, Woodburn, Patrick, Elliott, Alison M., Muhangi, L, Morison, Linda A., Ameke, Christine, Ornoding, N, Mpairwe, H, Woodburn, P, Morison, Linda A, Dennison Kizito, Omara, M, Omara, Mildred, Christine Ameke, Harriet Mpairwe, Linda A. Morison   +31 more
core   +2 more sources

Targeting B‐Cell‐Activating Factor and Its Receptor in Immune Thrombocytopenia and Warm Autoimmune Hemolytic Anemia

American Journal of Hematology, EarlyView.
ABSTRACT Current treatments for immune thrombocytopenia (ITP) and warm autoimmune hemolytic anemia (wAIHA), rare autoimmune diseases in which autoreactive B cells play a major role, can lead to high response rates; however, for many patients these responses are not durable or maintained after treatment discontinuation.
Matthieu Mahévas, Nichola Cooper, Vickie McDonald, Karina Yazdanbakhsh, Wilma Barcellini   +4 more
wiley   +1 more source