Results 151 to 160 of about 355,419 (303)

GLP‐1 agonists and the gut microbiome: A bidirectional relationship

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Glucagon‐like peptide‐1 (GLP‐1) receptor agonists have transformed the management of type 2 diabetes mellitus (T2DM) and obesity, yet their interactions with the gut microbiome remain an emerging frontier in pharmacological and metabolic research.
Srinivas Kamath   +2 more
wiley   +1 more source

All You Can Eat Yeast: Substituting Hexose Transporters With AtSWEET7 Alleviates Glucose Repression, Enabling Simultaneous Utilization of Sugars in Renewable Feedstocks

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Yeast sugar transporters have highly evolved for preferential glucose transport, a significant roadblock for utilizing non‐glucose sugars in renewable feedstocks such as lignocellulosic biomass. To enable simultaneous transport of multiple sugars, native hexose transporters were replaced by SWEET7p from Arabidopsis thaliana in engineered ...
Nurzhan Kuanyshev   +6 more
wiley   +1 more source

Nanomaterials‐mediated glycolysis rewriting to potentiate tumor immunotherapy

open access: yesBMEMat, EarlyView.
This review systematically summarizes cutting‐edge advances in glycolysis‐rewiring nanomedicines, emphasizing their mechanisms in reversing immunosuppression and reinvigorating antitumor immune responses. Challenges in clinical translation and future directions for designing multifunctional metabolic‐immune modulators are also critically discussed ...
Zilin Ma   +9 more
wiley   +1 more source

Subterranean environments contribute to three‐quarters of classified ecosystem services

open access: yesBiological Reviews, EarlyView.
ABSTRACT Beneath the Earth's surface lies a network of interconnected caves, voids, and systems of fissures forming in rocks of sedimentary, igneous, or metamorphic origin. Although largely inaccessible to humans, this hidden realm supports and regulates services critical to ecological health and human well‐being.
Stefano Mammola   +30 more
wiley   +1 more source

Tropical leg lymphedema caused by podoconiosis is associated with increased colonisation by anaerobic bacteria. [PDF]

open access: yesSci Rep, 2023
Neidhöfer C   +14 more
europepmc   +1 more source

Analysis of the economic viability and environmental impacts of a conceptual process model for the recovery of lactic acid from spent media in cultivated meat production

open access: yesBiotechnology Progress, EarlyView.
Abstract Scaled production of cultivated meat (CM) will co‐produce large volumes of spent media. Recycling of abundant metabolites such as lactic acid in spent media offers an opportunity for valorization and reduction of the carbon footprint of CM production; however, the feasibility has yet to be examined.
Josh Wimble   +2 more
wiley   +1 more source

Prevalence of Anaerobic and Aerobic Bacteria in Early Onset Neonatal Sepsis

open access: yesIranian Journal of Public Health, 2008
Background: To determine prospectively the prevalence of anaerobic and aerobic infection in early onset (during 72 hours of age) neonatal sepsis, in Tehran Vali-e-Asr Hospital.
F Nili   +4 more
doaj  

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