Results 151 to 160 of about 480,268 (357)

Microbiota humanization drives human‐like metabolic and immune transcriptomic shifts in pigs

open access: yesiMetaOmics, EarlyView.
This study successfully established gut microbiota‐humanized pigs, achieved human‐like remodeling of the serum metabolome, and uncovered transcriptional alterations in immune cell subsets. These findings advance our understanding of how human gastrointestinal microorganisms affect host metabolism and the immune function in a porcine model.
Zhaoqi Zhang   +9 more
wiley   +1 more source

Gut microbiota‐derived butyric acid regulates calcific aortic valve disease pathogenesis by modulating GAPDH lactylation and butyrylation

open access: yesiMeta, EarlyView.
Multi‐omics sequencing and correlation analysis identified the beneficial role of Faecalibacterium prausnitzii (F. prausnitzii)‐derived butyric acid (BA) as a key metabolite in the restoration of valve function in calcific aortic valve disease (CAVD). The therapeutic efficacy of BA in attenuating CAVD progression was confirmed in vitro, ex vivo, and in
Chunli Wang   +18 more
wiley   +1 more source

A gut microbiota‐bile acid axis inhibits the infection of an emerging coronavirus by targeting its cellular receptor aminopeptidase N

open access: yesiMeta, EarlyView.
Bacteroides fragilis employs bile salt hydrolase to reprogram host bile acid metabolism, generating lithocholic acid that directly blocks porcine deltacoronavirus infection by disrupting spike protein‐aminopeptidase N binding, defining a microbiota‐bile acid antiviral axis with therapeutic potential against coronaviruses.
Ya‐Qing Zhang   +12 more
wiley   +1 more source

Akkermansia muciniphila‐derived hypoacylated rough‐type lipopolysaccharides alleviate diet‐induced obesity via activation of TLR4−IL‐23−IL‐22 immune axis

open access: yesiMeta, EarlyView.
This study demonstrates that hypoacylated, rough‐type lipopolysaccharides (LPS) derived from Akkermansia muciniphila strain HW07 (ALPS) alleviates diet‐induced obesity. ALPS acts as a weak TLR4 agonist and significantly reduces weight gain, improves metabolic parameters, and restores gut barrier integrity in obese mice.
Li Sun   +14 more
wiley   +1 more source

The Future of Anaerobic Digestion: Challenges and Opportunities. [PDF]

open access: yesBioengineering (Basel)
Nikolausz M, Kornatz P.
europepmc   +1 more source

Effects of temperature on biofilm formation and resource recovery during anoxyphototrophic treatment of fuel‐synthesis wastewater

open access: yesJournal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND Fuel‐synthesis wastewater (FSW), a byproduct of the Fischer‐Tropsch process, requiring efficient treatment and resource recovery strategies. This study aimed to optimize temperature conditions for purple non‐sulfur bacteria (PNSB) biofilm formation and bioproduct recovery while simultaneously treating FSW. Experiments were conducted
Sultan Shaikh   +4 more
wiley   +1 more source

Open-Source Anaerobic Digestion Modeling Platform, Anaerobic Digestion Model No. 1 Fast (ADM1F). [PDF]

open access: yesBiotechnol Bioeng
Zhu K   +7 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy