Results 151 to 160 of about 1,338,164 (356)

Engineering Bacteria as Living Therapeutics in Cancer Therapy

open access: yesAdvanced Science, EarlyView.
Through synthetic biology approaches, natural bacteria can be genetically programmed into multifunctional living therapeutics. These engineered bacteria are capable of secreting anti‐tumor factors, displaying tumor‐associated antigens on their surface, or undergoing programmed self‐lysis to release therapeutic cargo.
Jiangfeng Chen   +6 more
wiley   +1 more source

Synergistic Promotion of Triple‐Negative Breast Cancer Tumorigenesis and Metastasis by Oral Polystyrene Nanoplastics Exposure via Alloprevotella‐Derived Glutamate and Platelet Activation

open access: yesAdvanced Science, EarlyView.
Polystyrene nanoplastics (PS‐NPs) administered via oral exposure accelerate triple‐negative breast cancer (TNBC) progression by synergistically modulating gut microbiota‐derived glutamate production and platelet activation. This study uncovers a pivotal crosstalk between microbial metabolites and platelet‐tumor interactions, offering mechanistic ...
Leilei Zhu   +9 more
wiley   +1 more source

Is skeletal muscle damaged by the oxidative stress following anaerobic exercise? [PDF]

open access: green, 2001
Hiroshi Ihara   +5 more
openalex   +1 more source

Smart Gated Hollow Mesoporous Silica Hydrogel for Targeting Endoplasmic Reticulum Stress and Promoting Periodontal Tissue Regeneration

open access: yesAdvanced Science, EarlyView.
The hollow mesoporous silica loaded with quercetin (HM‐QU@PEG) is combined with a thermosensitive anti‐bacterial matrix (TF127) to prepare HQUP@TF127. HQUP@TF127 effectively eliminates excessive ROS, alleviates endoplasmic reticulum stress, relieves mitochondrial calcium overload, and blocks the p53‐dependent apoptotic cascade. Furthermore, it enhances
Guichun Wang   +14 more
wiley   +1 more source

Changes in muscle damage enzymes inactive overweight male students after exhausted aerobic and anaerobic exercise

open access: yesمجله دانشگاه علوم پزشکی بیرجند, 2017
Background and Aim: Since the intensity and duration of exercise and recovery time are one of the influencing factors on injuries and adaptations, the current study examined changes in muscle damage active in overweight male students after exhaustive ...
Asma Soleimani   +2 more
doaj  

Influence of Warm-Up Music Preference on Anaerobic Exercise Performance in Division I NCAA Female Athletes. [PDF]

open access: yesJ Funct Morphol Kinesiol, 2021
Meglic CE   +4 more
europepmc   +1 more source

Metabolic Interplay in Acute Lung Injury: PARK7 Integrates FADS1/2‐Dependent PUFA Metabolism and H3K14 Lactylation to Attenuate Endothelial Ferroptosis and Dysfunction

open access: yesAdvanced Science, EarlyView.
SCAP/ARDS patients show reduced unsaturated fatty acids (UFAs) but higher PARK7 and lactate in plasma. PARK7 correlates positively with lactate and negatively with UFAs. Pulmonary endothelial cell multi‐omics show FADS1/2 downregulation and impaired PUFA metabolism. Lactate boosts PARK7 via H3K14 lactylation, and PARK7 then restores FADS1/2.
Jian Xu   +11 more
wiley   +1 more source

The Effect of High Intensity Aerobic and Anaerobic Training on the Memory of Healthy People

open access: yesAnnals of Applied Sport Science, 2017
Background. The evidence indicates that physical activity increases memory and ability to learn in human and animal. That is to say, the brain remarkably responds to exercise. Objectives.
Mohammad Rashidi   +2 more
doaj  

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