Results 201 to 210 of about 335,029 (357)
P53 Orchestrates Cancer Metabolism: Unveiling Strategies to Reverse the Warburg Effect [PDF]
arXivCancer cells exhibit significant alterations in their metabolism, characterised by a reduction in oxidative phosphorylation (OXPHOS) and an increased reliance on glycolysis, even in the presence of oxygen. This metabolic shift, known as the Warburg effect, is pivotal in fuelling cancer's uncontrolled growth, invasion, and therapeutic resistance.
arxiv
Apnoea as a novel method to improve exercise performance: A current state of the literature
Experimental Physiology, EarlyView.Abstract Acute breath‐holding (apnoea) induces a spleen contraction leading to a transient increase in haemoglobin concentration. Additionally, the apnoea‐induced hypoxia has been shown to lead to an increase in erythropoietin concentration up to 5 h after acute breath‐holding, suggesting long‐term haemoglobin enhancement.
Janne Bouten +4 more
wiley +1 more source
Petri nets in modelling glucose regulating processes in the liver [PDF]
arXivDiabetes is a chronic condition, considered one of the civilization diseases, that is characterized by sustained high blood sugar levels. There is no doubt that more and more people is going to suffer from diabetes, hence it is crucial to understand better its biological foundations.
arxiv
Experimental Physiology, EarlyView.Abstract To investigate the acute effects of hypoxia applied during discrete work and recovery phases of a perceptually regulated, high‐intensity interval exercise (HIIE) on external and internal loads in inactive overweight individuals. On separate days, 18 inactive overweight (28.7 ± 3.3 kg m−2; 31 ± 8 years) men and women completed a cycling HIIE ...
Jacky Soo +5 more
wiley +1 more source
The effect of ergosterol and ergocalciferol on the anaerobic glycolysis of rat-liver slices [PDF]
, 1955 G. N. Festenstein
openalex +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Placental mitochondrial adaptation to gestational hypoxia. Hypoxic pregnancy in sheep increases placental insulin like growth factor 2 (IGF2) signalling (1), which is associated with a shift in capacity away from β‐oxidation (2) and complex I‐mediated respiration (3), while maintaining total oxidative phosphorylation capacity (4).
Wen Tong +18 more
wiley +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Diabetes mellitus is associated with vascular pathology that leads to vascular complications in several tissues, such as retinopathy of the eye. Endothelial dysfunction plays a pivotal role in the progression of each complication.
C. McAleese +5 more
wiley +1 more source