Results 201 to 210 of about 70,398 (322)

Multi‐Omics Analysis Reveals Photodynamic Therapy Ameliorating Skin Photoaging by Improving Cellular Senescence Through Mitohormesis‐Mediated Reduction of Citrate Content

open access: yesAging Cell, Volume 25, Issue 1, January 2026.
Ultraviolet‐induced skin photoaging involves cellular senescence. Low‐dose photodynamic therapy (PDT) counteracts this by triggering mitochondrial ROS and mitohormesis, which improve metabolism and ameliorate senescence, leading to reduced wrinkles and enhanced skin barrier.
Yu Yan   +9 more
wiley   +1 more source

Photodynamic Therapy Enhances the Cytotoxicity  Of  Temozolomide  Against Glioblastoma Via Reprogramming Anaerobic Glycolysis

open access: green, 2022
Yongzhe Li   +7 more
openalex   +1 more source

Human hypoxia models in aerospace medicine: Potential applications for human pharmacological research

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 1, Page 58-72, January 2026.
Aerospace medicine required controlled terrestrial models to investigate influences of altered atmosphere conditions, such as hypoxia, on human health and performance. These models could potentially be expanded to encompass disease conditions or treatment targets regulated through hypoxia or hypercapnia.
Titiaan E. Post   +4 more
wiley   +1 more source

Paradoxical mitochondrial effects of nitric oxide synthase inhibition following oxygen–glucose deprivation–reoxygenation (OGD/R) in endothelial cells and neurons

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 2, Page 349-363, January 2026.
Background and Purpose Current dogma in stroke is that neuronal nitric oxide synthase (NOS1) exacerbates ischaemic brain injury, while endothelial nitric oxide synthase (NOS3) is protective. However, oxidative stress from ischaemia–reperfusion and oxygen–glucose deprivation‐reoxygenation (OGD/R) is known to uncouple NOS, leading to increased production
Venkata N. Sure   +5 more
wiley   +1 more source

Hyper- and hypo- nutrition studies of the hepatic transcriptome and epigenome suggest that PPARα regulates anaerobic glycolysis. [PDF]

open access: yesSci Rep, 2017
Soltis AR   +8 more
europepmc   +1 more source

ANAEROBIC GLYCOLYSIS BY ENZYME PREPARATIONS OF BRUCELLA SUIS

open access: yesJournal of Biological Chemistry, 1952
W G, ROESSLER   +3 more
openaire   +2 more sources

Comparative metabolomic and transcriptomic analysis of 2D and 3D mesenchymal stem cell cultures for improved therapeutic applications

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 2, Page 379-392, January 2026.
Comparative metabolomic and transcriptomic profiling reveals distinct metabolic shifts and reduced proliferation in 3D MSC spheroids, providing insights to optimise MSC‐based therapies. Abstract Background and Purpose Mesenchymal stem cells (MSCs) are used widely in regenerative medicine due to their multipotency and immunomodulatory properties ...
Manju Shrestha   +7 more
wiley   +1 more source

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