Results 261 to 270 of about 70,398 (322)

Impaired Cardiorespiratory Fitness in Type 1 Diabetes Is Associated With Metabolic Inflexibility and Specific Factors According to Sex

open access: yesJournal of Diabetes, Volume 17, Issue 12, December 2025.
Design and main findings of the study. ABSTRACT Background People with long‐term type 1 diabetes have reduced cardiorespiratory fitness (CRF). We aimed to assess the influence of body composition, energy substrate use, and blood glucose control on cardiopulmonary exercise test performance in subjects with uncomplicated, long‐term type 1 diabetes ...
Liliana Muñoz‐Hernandez   +14 more
wiley   +1 more source

NADPH oxidase isoform NOX-2 deficiency affects mitochondrial oxygen consumption and metabolic flexibility. [PDF]

open access: yesRedox Biol
Thetchinamoorthy K   +6 more
europepmc   +1 more source

Changes in Environmental Conditions Differentially Affect the Bacterial Microbiome Communities in Different Apple Fruit Tissues

open access: yesEnvironmental Microbiology Reports, Volume 17, Issue 6, December 2025.
This study investigates the bacterial communities in ‘Honeycrisp’ apples in Atlantic Canada, highlighting how weather, and farming practices shape these communities in different fruit tissues. Weather impacts core and peel tissues bacteria differently across growing seasons, identifies key microbes in microbial interaction networks, and provides ...
Michael S. Mclaughlin   +3 more
wiley   +1 more source

Microbial Community Composition and Function in Jiangsu Oil Reservoir Cores, China

open access: yesEnvironmental Microbiology Reports, Volume 17, Issue 6, December 2025.
Shale oil reservoirs meet the basic requirements for microbial growth. Microorganisms, crude oil and water are distributed within the pore spaces of the reservoir formation. In situ microorganisms utilise crude oil for growth and reproduction. ABSTRACT Shale oil reservoirs are typically characterised by elevated temperatures, confined spaces and ...
Bo‐Wen Wang   +10 more
wiley   +1 more source

Microbial and Metabolic Disorders in Cervical Cancer: Structural Insights, Biomarkers, Mechanisms, and Therapeutic Strategies

open access: yesCancer Science, Volume 116, Issue 12, Page 3228-3238, December 2025.
We unravel synergistic mechanisms by which microbial‐host metabolic networks regulate the tumor immune microenvironment and therapy resistance, bridging gaps between microbiota research and cancer metabolism. Identified biomarkers (e.g., Lactobacillus, C8‐ceramide‐1‐phosphate) and therapeutic approaches (e.g., FMT combined with immune checkpoint ...
Hong Tao   +6 more
wiley   +1 more source

FAM111B Suppression Enhances Sensitivity to Gemcitabine in Pancreatic Cancer Through Intracellular pH Regulation

open access: yesCancer Science, Volume 116, Issue 12, Page 3519-3531, December 2025.
Family with Sequence Similarity 111 Member B (FAM111B), cysteine/serine peptidase with molecular targets, are upregulated under acidic conditions. FAM111B suppression increased the sensitivity to gemcitabine through intracellular pH regulation. Moreover, FAM111B expression is correlated with poorer overall survival in pancreatic cancer patients ...
Motonobu Nishimura   +9 more
wiley   +1 more source

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