Results 251 to 260 of about 1,576,643 (363)

High‐Altitude Adaptation of Frogs (Case Study: Nanorana parkeri): From Physiological Phenotypes to AltitudeOmics

open access: yesIntegrative Zoology, EarlyView.
High altitudes are challenging for the animals that inhabit these environments. The Xizang plateau frog (Nanorana parkeri) survives in high‐altitude environments through a synergistic strategy of metabolic remodeling and protein expression adjustment to optimize energy efficiency and enhance cellular protection.
Xuejing Zhang   +6 more
wiley   +1 more source

Analysis of Heart Rate Deflection Points to Predict the Anaerobic Threshold by a Computerized Method

open access: yesJournal of Strength and Conditioning Research, 2012
S. Marques-Neto   +3 more
semanticscholar   +1 more source

Cenozoic Tectonics Ignite Mitochondrial Codon Innovations Propelling Canid Body Size Evolution and Transcontinental Radiations

open access: yesIntegrative Zoology, EarlyView.
We decode mitochondrial genomes across all extant canids, revealing lineage‐specific codon optimization driven by altitude, predation, and body size. A tripartite framework integrates geological events, metabolic constraints, and adaptive radiation to explain carnivore evolution.
Xiaoyang Wu   +8 more
wiley   +1 more source

Peri‐operative rehabilitation in patients undergoing elective cardiac valve surgery: a randomised controlled trial

open access: yesAnaesthesia, EarlyView.
Summary Introduction Patients with valvular heart disease are at high risk of postoperative pulmonary complications, which contribute to morbidity and mortality. However, few studies have focused specifically on peri‐operative rehabilitation in this patient population.
Yuting Liu   +16 more
wiley   +1 more source

Living by the lake: Plant food diversity in a prehistoric lake‐dwelling community in the Republic of North Macedonia

open access: yesArchaeometry, EarlyView.
Abstract This paper explores the relationship between wetland ecosystems and prehistoric lakeshore settlements within the Lake Ohrid basin (a biodiversity hotspot) by considering plant food systems at Ploča Mičov Grad, North Macedonia. The mid‐fifth millennium (c.4555–4373 to 4437–4241 cal BCE) waterlogged assemblage contained a diverse spectrum of ...
Amy Holguin   +14 more
wiley   +1 more source

Untangling nutrient co‐regulation of ombrotrophic peatland development

open access: yesBoreas, EarlyView.
Multi‐method (FTIR, FT‐NIR and TGA) approaches characterizing the organic peat constituents at Holcroft Moss reveal a record of switches that reflect broadly hydroclimate variability governing the decomposition patterns. There are periods, however, where hydroclimate does not fully explain the variability observed and instead changes appear linked to ...
Richard C. Chiverrell   +6 more
wiley   +1 more source

The impact of Foxp3+ regulatory T‐cells on CD8+ T‐cell dysfunction in tumour microenvironments and responses to immune checkpoint inhibitors

open access: yesBritish Journal of Pharmacology, EarlyView.
Immune checkpoint inhibitors (ICIs) have been a breakthrough in cancer therapy, inducing durable remissions in responding patients. However, they are associated with variable outcomes, spanning from disease hyperprogression to complete responses with the onset of immune‐related adverse events.
Mikhaël Attias, Ciriaco A. Piccirillo
wiley   +1 more source

The return of metabolism: biochemistry and physiology of glycolysis

open access: yesBiological Reviews, EarlyView.
ABSTRACT Glycolysis is a fundamental metabolic pathway central to the bioenergetics and physiology of virtually all living organisms. In this comprehensive review, we explore the intricate biochemical principles and evolutionary origins of glycolytic pathways, from the classical Embden–Meyerhof–Parnas (EMP) pathway in humans to various prokaryotic and ...
Nana‐Maria Grüning   +19 more
wiley   +1 more source

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