Results 191 to 200 of about 27,150 (219)

Efficacy and safety of anakinra in radiation-induced acute pericarditis: a case report. [PDF]

Front Cardiovasc Med
Sicignano LL, Murace CA, Palazzo A, Verrecchia E, Massaro MG, Manna R, Gerardino L.   +6 more
europepmc   +1 more source

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Anakinra

BioDrugs, 2002
Anakinra, a recombinant human interleukin-1 (IL-1) receptor antagonist, is the first biological agent approved to block the pro-inflammatory effects of IL-1 in patients with rheumatoid arthritis. In a double-blind, randomised trial in 472 patients with active, severe or very severe rheumatoid arthritis, recipients of subcutaneous anakinra 150 mg/day ...
Gillian M. Keating, Risto S Cvetković
  +10 more sources

Anakinra-Associated Amyloidosis

JAMA Dermatology, 2022
This case report describes 2 patients with iatrogenic amyloidosis secondary to subcutaneous injections of anakinra to manage neonatal-onset multisystem inflammatory disease.
Sara, Alehashemi, Surendra, Dasari, Adriana A, de Jesus, Edward W, Cowen, Chia-Chia Richard, Lee, Raphaela, Goldbach-Mansky, Ellen D, McPhail   +6 more
openaire   +2 more sources

Treatment of osteoarthritis with anakinra

Current Rheumatology Reports, 2007
Osteoarthritis (OA) is the most common form of arthritis and one of the leading causes of disability worldwide. The incidence of OA increases with age, and as longevity increases, it will cause a significant socioeconomic burden. No disease-modifying therapy is available for OA.
Roy Fleischmann, Imran Iqbal
openaire   +3 more sources

Rasmussen’s syndrome treated with anakinra

Journal of Neurology, 2023
Rasmussen's encephalitis (RE) is a rare chronic neurological disorder, characterized by unilateral inflammation of the cerebral cortex, refractory focal epilepsy or epilepsia partialis continua, hemiparesis, and progressive cognitive decline. Interleukin-1 (IL-1) plays an important role in neuroinflammation as a key element in the activation of the ...
Abdullah Arcan, Esra Koçhan Kızılkılıç, Ayşegül Gündüz, Rümeysa Unkun, Annamaria Vezzani, Çiğdem Özkara   +5 more
openaire   +2 more sources

Anakinra for rheumatoid arthritis

Cochrane Database of Systematic Reviews, 2009
In the past decade, a novel class of therapies directed against specific cytokines implicated in the disease process of rheumatoid arthritis (RA), called the 'Biologics' have greatly improved and expanded treatment for RA. Anakinra is an interleukin-1 receptor antagonist that is currently FDA-approved for moderate-severe RA that has been unresponsive ...
Marty T. Mertens, Jasvinder A. Singh
openaire   +3 more sources