Results 101 to 110 of about 101,184 (301)

Clinical Advances and Challenges in Dose Constraints for Organs at Risk in Proton Therapy: A Systematic Review of the Last Decade's Literature

open access: yesPrecision Radiation Oncology, EarlyView.
This systematic review synthesizes decade‐long evidence from peer‐reviewed literature and clinical guidelines, critically evaluating current understanding of OARs tolerance in proton therapy. Abstract Proton beam therapy has demonstrated significant clinical efficacy across multiple malignancies, primarily attributed to its distinct physical dose ...
Jinghao Duan   +10 more
wiley   +1 more source

Anal canal development in the embryonic and early foetal period [PDF]

open access: yes, 2003
The aim of study is to investigate the development of the anal canal in human embryos and foetuses. In embryos at stage 19 the boundary between the ectodermal and endodermal linings of the anal canal is located just below the level of the internal anal ...
Korzeniowska-Kromer, Ewa, Kromer, Piotr
core   +1 more source

Late Bowel Symptoms in Long‐Term Survivors of Prostate Cancer Following Radiotherapy

open access: yesThe Prostate, EarlyView.
ABSTRACT Background Despite advances in radiotherapy planning, some long‐term prostate cancer survivors experience persistent symptoms. Although overall quality of life appears comparable between patients treated with definitive and salvage radiotherapy and aligns with normative data, prostate‐specific deficits—particularly bowel symptoms—may persist ...
Isabella Gruber   +2 more
wiley   +1 more source

Volumetric Changes in Perianal Fistulizing Crohn's Disease Measured by Magnetic Resonance Is Feasible and Could Be a Potential Biomarker to Predict Clinical Outcomes

open access: yesUnited European Gastroenterology Journal, EarlyView.
ABSTRACT Background and Aim Changes in 3D volumetry of perianal fistulas in patients with Crohn's disease (CD) measured by MRI could be an imaging biomarker of interest. The objective of the study was to determine the value of volumetric changes in CD perianal fistulas after medical treatment to predict outcomes.
Berta Caballol   +11 more
wiley   +1 more source

Effectiveness and Safety of Advanced Dual‐Targeted Therapy in Refractory Perianal Crohn's Disease

open access: yesUnited European Gastroenterology Journal, EarlyView.
ABSTRACT Introduction Perianal Crohn's disease (CD) remains challenging to treat despite the increasing number of advanced therapies. Advanced dual‐targeted therapy has emerged as a new treatment option in CD, but no data are available for perianal CD. The aim of this study was to evaluate the effectiveness and safety of advanced dual‐targeted therapy ...
Nadia Fathallah   +9 more
wiley   +1 more source

Anal canal adenocarcinoma with a late brain metastatic lesion – a case report

open access: yesJournal of Coloproctology, 2019
Herein we present a rare case of anal canal adenocarcinoma manifesting as non-healing perianal abscess that subsequently underwent radiochemotherapy followed by abdominoperineal resection for residual disease.
Ashraf Imam   +6 more
doaj  

Evaluation of Langerhans cells counts comparing HIV-positive and negative anal squamous cell-carcinoma patients Avaliação das células de Langerhans no carcinoma espinocelular do canal anal em pacientes HIV-positivo e negativo

open access: yesActa Cirúrgica Brasileira, 2012
PURPOSE: To investigate the differences in Langerhans cells (LCs) populations between HIV-positive and negative anal squamous cell carcinomas patients. METHODS: Twenty five patients (14 HIV-positive and 11 HIV-negative) were evaluated.
Sylvia Heloisa Arantes Cruz   +3 more
doaj   +1 more source

Neuroendocrine tumor of the anal canal

open access: yesGE Jornal Português de Gastrenterologia, 2012
AbstractWe report a rare case of neuroendocrine tumor of the anal canal and its poor prognosis, plus discuss the need of immunohistochemical for an acurate diagnosis and to guide treatment.
Amanda Pires Barbosa   +7 more
openaire   +2 more sources

A persistent hymen resulting in an open cervix but closed pyometra and pyocolpos in a mixed‐breed female domestic dog

open access: yesVeterinary Record Case Reports, EarlyView.
Abstract A rescued mixed‐breed (Africanis type), entire, female dog, approximately 2 years old, with an unknown history, presented with a prominent perineal swelling between the anus and vulva. Ultrasound identified it as a fluid‐filled structure, and an aspirate revealed an exudate consisting of degenerate neutrophils, bacterial cocci and rods.
Taylor June Kruger   +4 more
wiley   +1 more source

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