Acute hot‐water immersion augments the diastolic blood pressure nocturnal dip in healthy adults
Abstract Hot‐water immersion (HWI) has been shown to reduce 24 h ambulatory systolic blood pressure in hypertensive adults and might represent a preventative strategy for maintaining cardiovascular health in normotensive adults. The purpose of this study was to determine the time course of post‐HWI hypotension and test the hypothesis that a single HWI ...
Samuel F. Leaney +8 more
wiley +1 more source
Abstract The objective of this study was to investigate thermophysiological and perceptual responses to exercise heat stress in people with cystic fibrosis (pwCF) on Elexacaftor/Tezacaftor/Ivacaftor (ETI) versus healthy controls, and to explore their lived experiences of heat stress.
Lauren J. Clayton +10 more
wiley +1 more source
Manometric and Sonographic Examination of Anal Sphincter Complex, Fecal Incontinence and Quality of Life Outcomes in Fournier's Gangrene Survivors. [PDF]
Işık Ö +7 more
europepmc +1 more source
Abstract The independent effects of different cooling practices, such as cold‐water immersion (CWI), on thermal and cardiovascular responses to sauna remain unclear. This study tested the hypothesis that thermal and cardiovascular responses to sauna are attenuated when CWI was included in a cooling break compared to cooling in air only.
Tomos F. Owen +4 more
wiley +1 more source
Feasibility and reproducibility of a novel introital exo-anal ultrasound approach for assessment of the external anal sphincter. [PDF]
Youssef A +6 more
europepmc +1 more source
Abstract figure legend TMEM16A plays a pivotal role in setting the duration of the action potential plateau in human uterine smooth muscle. An increase in TMEM16A expression in labour underpins a lengthening of the plateau and this provides time for the contraction to become larger and longer, important for timely successful labour.
Helena C. Parkington +4 more
wiley +1 more source
A Single-Center Retrospective Cohort Study of Risk Factors for Obstetric Anal Sphincter Injury at a Tertiary Hospital in Japan. [PDF]
Goto D +8 more
europepmc +1 more source
Update on cellular expression and function of ANO1 channels in urethral smooth muscle
Abstract figure legend Activation of ANO1 channels and resulting Cl− efflux are suggested to modulate urethral smooth muscle contractility by enhancing Ca2+ influx via voltage‐dependent Ca2+ entry and resulting contraction in urethral smooth muscle cells.
Bernard T. Drumm, Neha Gupta
wiley +1 more source
WNT3a induces external anal sphincter fibrosis and dysfunction in rabbits. [PDF]
Thippeswamy J +6 more
europepmc +1 more source
Maximal exercise at high altitude does not exacerbate inflammation in the human brain
Abstract figure legend This study investigated arterial–internal jugular venous (IJV) exchange of cytokines in response to low‐intensity and maximal cycling exercise at sea level and following 6–8 days at 3800 m a.s.l. There was a shift towards net release of interleukin‐6 (IL‐6), interleukin‐8 (IL‐8), monocyte chemoattractant protein‐1 (MCP‐1) and ...
Hannah G. Caldwell +11 more
wiley +1 more source

