Results 1 to 10 of about 472,840 (425)

Incidence and risk factors associated with negative postoperative behavioral changes in children undergoing painless gastroscopy

open access: yesBMC Pediatrics, 2023
Objective To investigate the incidence of and risk factors associated with negative postoperative behavioral changes (NPOBCs) in children undergoing painless gastroscopy.
Pu YanYing   +7 more
doaj   +1 more source

Cervical sympathetic trunk transection alleviates acute lung injury caused by intestinal obstruction via inhibition of phospholipase A2 in rats

open access: yesBMC Anesthesiology, 2022
Background Intestinal obstruction can result in inflammatory injury to distant organs, especially the lungs. Stellate ganglion block (SGB) provides sympathetic nervous homeostasis and inhibits the systemic inflammatory response.
Zhengfeng Gu   +7 more
doaj   +1 more source

Bilateral superficial cervical plexus block with conscious sedation for thyroid surgery

open access: yesBangabandhu Sheikh Mujib Medical University Journal, 2022
Total thyroidectomy can safely be performed by bilateral superficial cervical plexus blockade which is a regional anesthetic technique to anaesthetize superficial branches of the anterior primary rami of cervical 3-5 spinal nerves.
Mohammad Ahad Hossain   +6 more
doaj   +1 more source

In-Depth Characterization of Somatic and Orofacial Sensitive Dysfunctions and Interfering-Symptoms in a Relapsing-Remitting Experimental Autoimmune Encephalomyelitis Mouse Model

open access: yesFrontiers in Neurology, 2022
Among the many symptoms (motor, sensory, and cognitive) associated with multiple sclerosis (MS), chronic pain is a common disabling condition. In particular, neuropathic pain symptoms are very prevalent and debilitating, even in early stages of the ...
Amélie Démosthènes   +6 more
doaj   +1 more source

Metabolically Stable Neurotensin Analogs Exert Potent and Long-Acting Analgesia Without Hypothermia [PDF]

open access: yesBehavioural Brain Research, 405:113189 (2021), 2021
The endogenous tridecapeptide neurotensin (NT) has emerged as an important inhibitory modulator of pain transmission, exerting its analgesic action through the activation of the G protein-coupled receptors, NTS1 and NTS2. Whereas both NT receptors mediate the analgesic effects of NT, NTS1 activation also produces hypotension and hypothermia, which may ...
arxiv   +1 more source

Epidural versus non-epidural or no analgesia for pain management in labour.

open access: yesCochrane Database of Systematic Reviews, 2018
BACKGROUND Epidural analgesia is a central nerve block technique achieved by injection of a local anaesthetic close to the nerves that transmit pain, and is widely used as a form of pain relief in labour.
M. Anim-Somuah   +3 more
semanticscholar   +1 more source

Reliability of pleth variability index in predicting preload responsiveness of mechanically ventilated patients under various conditions: a systematic review and meta-analysis

open access: yesBMC Anesthesiology, 2019
Background Goal-directed volume expansion is increasingly used for fluid management in mechanically ventilated patients. The Pleth Variability Index (PVI) has been shown to reliably predict preload responsiveness; however, a lot of research on PVI has ...
Tianyu Liu   +4 more
doaj   +1 more source

Antinociceptive tolerance to NSAIDs in the anterior cingulate cortex is mediated via endogenous opioid mechanism

open access: yesBMC Pharmacology and Toxicology, 2018
Background In the past decade several studies have reported that in some brain areas, particularly, in the midbrain periaqueductal gray matter, rostral ventro-medial medulla, central nucleus of amygdala, nucleus raphe magnus, and dorsal hippocampus ...
Nana Tsiklauri   +6 more
doaj   +1 more source

Cell-penetrating pepducins targeting the neurotensin receptor type 1 relieve pain [PDF]

open access: yesPharmacological Research. 104750 (2020), 2020
Pepducins are cell-penetrating, membrane-tethered lipopeptides designed to target the intracellular region of a G protein-coupled receptor (GPCR) in order to allosterically modulate the receptor's signaling output. In this proof-of-concept study, we explored the pain-relief potential of a pepducin series derived from the first intracellular loop of ...
arxiv   +1 more source

A prospective, multicentre, observational cohort study of analgesia and outcome after pneumonectomy [PDF]

open access: yes, 2011
Background Meta-analysis and systematic reviews of epidural compared with paravertebral blockade analgesia techniques for thoracotomy conclude that although the analgesia is comparable, paravertebral blockade has a better short-term side-effect profile ...
Berry, C.   +28 more
core   +1 more source

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