Results 91 to 100 of about 2,605 (195)

Novel approaches for drug development against chronic primary pain: A systematic review

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus   +5 more
wiley   +1 more source

Postoperative Care and Management in Pediatric Hematology‐Oncology Patients

open access: yesEuropean Journal of Haematology, EarlyView.
ABSTRACT Pediatric patients with hematologic and oncologic diseases often undergo surgical procedures as part of diagnosis and therapy. These include central venous catheter placements, tumor resections, lymph node and bone marrow biopsies, among others.
Shachi Srivatsa, Sara A. Mansfield
wiley   +1 more source

Needle bevel orientation does not affect diffusion of contrast medium during perineural injection of the lateral palmar/plantar nerve and lateral palmar metacarpal/plantar metatarsal nerves

open access: yesEquine Veterinary Education, Volume 38, Issue 7, Page e456-e463, July 2026.
Summary Background Perineural anaesthesia is used to localise pain in horses presenting with lameness. Diffusion of local anaesthetics during perineural analgesia complicates clinical interpretation. Needle bevel orientation has been shown to affect drug diffusion in humans.
V. Knopp   +6 more
wiley   +1 more source

Clinical correlates of women requesting labour epidural analgesia in a tertiary hospital in Nigeria

open access: yesNigerian Postgraduate Medical Journal, 2013
Objectives: To evaluate the clinical correlates of women who received pain relief in labour with lumbar epidural analgesia and also investigate the labour outcome.
C O Imarengiaye   +3 more
doaj  

Surgical excision of melanomas in the anal region and reconstruction of the anus in 11 horses

open access: yesEquine Veterinary Education, Volume 38, Issue 7, Page e387-e398, July 2026.
Summary This case report describes the surgical excision of large perianal and perineal melanomas, and reconstruction of the anus in 11 grey horses. Four horses had a history of painful defaecation or urination due to extensive tumours. Seven horses had no clinical signs at the time of admission but had rapidly growing nodules around the anus with ...
F. Somm, A. E. Fürst, M. A. Jackson
wiley   +1 more source

Analgesic effects of alpha‐2‐adrenoreceptor agonists in equine medicine: systemic, spinal, and local applications

open access: yesEquine Veterinary Education, EarlyView.
Summary Alpha‐2‐adrenoreceptor agonists provide analgesia when used as sole agents but can also be used in combination with other drugs for their additive and potentially synergistic effects. Further, because of their effects on blood flow, alpha‐2‐adrenoreceptor agonists act to extend and perhaps intensify the effects of drugs, such as local ...
J. Brandly   +4 more
wiley   +1 more source

Relation between epidural analgesia and perinatal outcomes on Robson class 2a

open access: yesAJOG Global Reports
BACKGROUND: : The use of epidural analgesia represents the gold standard for pain management during labor, however, the influence of the use of epidural analgesia on delivery mode and neonatal outcomes is not fully understood.
Serena Lecis, MD   +16 more
doaj   +1 more source

Surgical removal of a perirectal melanoma through sphincterotomy and rectal wall resection in a horse

open access: yesEquine Veterinary Education, EarlyView.
Summary Melanomas are among the most frequent neoplasms in grey horses. Deep perirectal melanomas, however, are uncommon and challenging to excise due to their proximity to the peritoneal reflection. This report describes the successful standing removal of a large (16 × 8 × 6 cm) perirectal melanoma firmly adherent to the dorsal rectal wall in a 19 ...
R. Becker, C. Koch, M. de Preux
wiley   +1 more source

Knowledge and Attitude about Labor Epidural Analgesia among Pregnant Women Attending Antenatal Clinic

open access: yesJournal of Nepal Health Research Council
Background: Labour pain is one of the most painful experiences that a woman faces in her lifetime. There are various options for labour pain management. Epidural analgesia is the gold standard method for pain management during labour.
Bashu Dev Parajuli   +7 more
doaj   +1 more source

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