Results 241 to 250 of about 120,880 (301)

Alkalinised lidocaine as an anaesthetic before onabotulinumtoxinA injections. a randomised trial

BJU International, Volume 135, Issue 4, Page 638-647, April 2025.
Objectives To evaluate the effect of intravesical alkalinised lidocaine as an anaesthetic treatment on procedural pain during intradetrusor onabotulinumtoxinA (BTX‐A) injections for overactive bladder. Patients and Methods This single‐centre, randomised, double‐blind, placebo‐controlled two period crossover trial was conducted on women scheduled for ...
Meryam El Issaoui, Marlene Elmelund, Niels Klarskov   +2 more
wiley   +1 more source

Appropriate Combination of Nalbuphine Combined With Esketamine for Weakly Opioid Anesthesia in Postlaparoscopic Cholecystectomy Analgesia: A Randomized Controlled Trial. [PDF]

Pain Res Manag
Zhang M, Wu H, Zheng H, Zhang J, Wang J, Luo H, Yang H.   +6 more
europepmc   +1 more source

Synergistic RU486 and olaparib therapy enhances apoptosis in endometriosis by simultaneously targeting hormonal signalling and DNA repair

British Journal of Pharmacology, EarlyView.
Background and Purpose Endometriosis is a chronic, hormone‐dependent disorder characterized by ectopic implantation of endometrial tissue, often accompanied by pain and infertility. Although the progesterone receptor modulator RU486 is effective for pain relief, its impact on lesion regression is limited, possibly due to apoptosis resistance and ...
Yujie Peng, Meng Zhang, Libo Zhu, Wenqiang Qian, Jingjing Yan, Huidi Jiang, Yu Xin, Ying Zhang, Dongli Sun, Weidong Fei, Mengdan Zhao   +10 more
wiley   +1 more source

Comparison of erector spinae plane block and rhomboid intercostal block for postoperative pain management in patients undergoing unilateral breast surgery. [PDF]

BMC Anesthesiol
Avcı G, Okan SC, Yörükoğlu HU, Aksu C, Kuş A.   +4 more
europepmc   +1 more source

Cancer pain: current practice and emerging targets

British Journal of Pharmacology, EarlyView.
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye, Marcin Chwistek, Zhiting Gong, Vanessa Uzonwanne, Xiaojie Shi, Arpad Szallasi   +5 more
wiley   +1 more source

Oliceridine versus Sufentanil for Postoperative Recovery and Opioid-Related Adverse Events in Patients Undergoing Thoracoscopic Lobectomy: A Randomized Double-Blind Controlled Trial. [PDF]

Drug Des Devel Ther
Hu N, Wang C, Zhang QQ, Zhang ZJ, Ding X, Zhang Y.   +5 more
europepmc   +1 more source

POSTOPERATIVE ANALGESIA IN CHILDREN

British Journal of Anaesthesia, 1993
openaire   +2 more sources

Liposomal bupivacaine versus standard ropivacaine for pain control in adults receiving continuous supraclavicular brachial plexus blocks for open elbow arthrolysis: study protocol for a randomised controlled non-inferiority clinical trial. [PDF]

BMJ Open
Luo T, Zheng S, Zhao Y, Yang X, Li X, Ji Y, Wang Y, Tang H, Xiao R, Zhang W, Li T, Wang G, Yuan Y.   +12 more
europepmc   +1 more source