Results 11 to 20 of about 407,236 (366)

TRPA1 Channel is Involved in SLIGRL-Evoked Thermal and Mechanical Hyperalgesia in Mice

open access: yesMedical Sciences, 2019
Persistent itch (pruritus) accompanying dermatologic and systemic diseases can significantly impair the quality of life. It is well known that itch is broadly categorized as histaminergic (sensitive to antihistamine medications) or non-histaminergic ...
Merab G. Tsagareli   +3 more
doaj   +1 more source

Effect of continuous intraoperative infusion of methoxamine on renal function in elderly patients undergoing gastrointestinal tumor surgery: a randomized controlled trial

open access: yesBMC Anesthesiology, 2020
Background Acute renal injury (AKI) caused by hypotension often occurs in elderly patients after gastrointestinal tumor surgery. Although vasoactive drugs can increase effective filtration pressure, they may increase renal vascular resistance and reduce ...
Xiaowei Guo   +6 more
doaj   +1 more source

Association Between Burst-Suppression Latency and Burst-Suppression Ratio Under Isoflurane or Adjuvant Drugs With Isoflurane Anesthesia in Mice

open access: yesFrontiers in Pharmacology, 2021
The same doses of anesthesia may yield varying depths of anesthesia in different patients. Clinical studies have revealed a possible causal relationship between deep anesthesia and negative short- and long-term patient outcomes. However, a reliable index
Di Wang   +13 more
doaj   +1 more source

Intraarticular Tramadol-Bupivacaine Combination Prolongs the Duration of Postoperative Analgesia After Outpatient Arthroscopic Knee Surgery [PDF]

open access: yes, 2008
BACKGROUND: Intraarticular (IA) local anesthetics are often used for the management and prevention of pain after arthroscopic knee surgery. Recently, IA tramadol was also used for the management of these patients.
Baraka, Anis   +6 more
core   +2 more sources

Manejo del dolor postoperatorio de cesárea: Estudio Observacional en el Instituto Nacional Materno Perinatal 2021

open access: yesRevista Peruana de Investigación Materno Perinatal, 2022
Objetivo. Describir los esquemas y efectividad del tratamiento del dolor postoperatorio en el Instituto Nacional Materno Perinatal. Materiales y Métodos.
Marleny Elizabeth Huayanay Bernabe   +5 more
doaj  

NSAIDs attenuate hyperalgesia induced by TRP channel activation

open access: yesData in Brief, 2016
Transient receptor potential (TRP) cation channels have been extensively investigated as targets for analgesic drug discovery. Because some non-steroidal anti-inflammatory drugs (NSAIDs) are structural analogs of prostaglandins (mediators of inflammation)
Ivliane Nozadze   +3 more
doaj   +1 more source

Opioid-free anaesthesia in three dogs [PDF]

open access: yesOpen Veterinary Journal, 2017
Opioid-free anaesthesia (OFA) is a relatively new and growing field in human medicine. There are multiple motivations behind this emerging practice with the recognition of several serious potential opioid-related adverse effects including opioid induced ...
Donna M. White   +2 more
doaj   +1 more source

The Antitumor Peptide ERα17p Exerts Anti-Hyperalgesic and Anti-Inflammatory Actions Through GPER in Mice

open access: yesFrontiers in Endocrinology, 2021
Persistent inflammation and persistent pain are major medical, social and economic burdens. As such, related pharmacotherapy needs to be continuously improved.
Christophe Mallet   +10 more
doaj   +1 more source

Ultrasound-Guided Lateral Femoral Cutaneous Nerve Cryoneurolysis for Analgesia in Patients With Burns. [PDF]

open access: yes, 2020
Autologous skin grafting from the thigh is frequently required for treatment of burns and is associated with intense pain at the donor site. Local anesthetic-based (LA) nerve blocks of the lateral femoral cutaneous nerve (LFCN) have been demonstrated to ...
Fiallo, Alfredo   +6 more
core  

Veterinarians in the UK on the use of non-steroidal anti-inflammatory drugs (NSAIDs) for post-disbudding analgesia of calves [PDF]

open access: yes, 2016
Top 20 down-regulated genes after DAPT treatment in P0 Lfng-GFP+ cells.
Andrew K. Groves (276455)   +10 more
core   +3 more sources

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