Results 211 to 220 of about 402,046 (367)

Trametinib in Adults with Neurofibromatosis Type 1‐Related Symptomatic Plexiform Neurofibromas

open access: yesAnnals of Neurology, EarlyView.
Objective Mitogen‐activated protein kinase kinase inhibitors have shown promising results in treatment of plexiform neurofibromas in neurofibromatosis type 1 patients, but data in adults are limited. The aim of this phase 2 study was to investigate the efficacy and safety of trametinib in adults with neurofibromatosis type 1.
D. Christine Noordhoek   +7 more
wiley   +1 more source

Global warming “heating up” the ICU through Candida auris infections: the climate changes theory

open access: yesCritical Care, 2019
Giovanni Misseri   +2 more
doaj   +1 more source

Chloroquine for COVID-19: rationale, facts, hopes

open access: yesCritical Care, 2020
Andrea Cortegiani   +3 more
doaj   +1 more source

Identification of New KCNT1‐Epilepsy Drugs by In Silico, Cell, and Drosophila Modeling

open access: yesAnnals of Neurology, EarlyView.
Objective Hyperactive KCNT1 potassium channels, caused by gain‐of‐function mutations, are associated with a range of epilepsy disorders. Patients typically experience drug‐resistant seizures and, in cases with infantile onset, developmental regression can follow.
Michael G. Ricos   +9 more
wiley   +1 more source

Is it time to consider visual feedback systems the gold standard for chest compression skill acquisition?

open access: yesCritical Care, 2017
Andrea Cortegiani   +5 more
doaj   +1 more source

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