Intraperitoneal ketamine versus bupivacaine for postoperative pain control after laparoscopic cholecystectomy - a double-blind randomized controlled trial. [PDF]
Bughio S +5 more
europepmc +1 more source
Recent Advances in Isatin–Thiazole Hybrids: Synthesis, Structural Design, and Biological Application
ABSTRACT Isatin–thiazole hybrids are considered privileged chemical scaffolds due to their broad spectrum of pharmacological properties, making them attractive candidates for drug development. As a result, isatin–thiazole derivatives have emerged as a prominent class of hybrid heterocycles and have been the focus of extensive research in recent years ...
Isadora M. G. Andrade +4 more
wiley +1 more source
It will happen once in a lifetime: learning from the SIAARTI survey on malignant hyperthermia clinical practices. [PDF]
Sbaraglia F.
europepmc +1 more source
ABSTRACT Oral mucositis is a frequent and painful complication of cancer therapy with limited effective options. This study evaluated a mucoadhesive polyvinyl alcohol (PVA) film containing 2.5% Fridericia chica extract as a novel strategy. The formulation was characterized for antioxidant activity, phenolic and flavonoid content, and reactive species ...
Ilza Maria de Oliveira Sousa +12 more
wiley +1 more source
Current Perspectives on Remifentanil-PCA for Labor Analgesia: A Narrative Review. [PDF]
Vovk Racman P +2 more
europepmc +1 more source
Hydroalcoholic crude extract of Persea cordata showed in its composition, the presence of lignans based on LCESIMS data. This crude extract displayed anti‐oedematogenic and antinociceptive activities in vivo. Abstract This study aimed to establish the chemical profile and evaluate the anti‐oedematogenic and analgesic activities of the hydroalcoholic ...
Valfredo Schlemper +6 more
wiley +1 more source
Sterile water injections for analgesia in renal colic: a meta-analysis of level 1 evidence. [PDF]
Perros I +5 more
europepmc +1 more source
The cis‐2,3‐bis(trifluoromethyl)cyclopropyl chemotype is introduced. The steric demand of this motif is intermediate between that of the heptafluoroisopropyl and prefluorotertbutyl groups; yet, it induces significantly less lipophilicity than these due to its facial polarity.
Daniel Gaviña +5 more
wiley +1 more source
Ultrasound-guided unilateral versus bilateral erector spinae plane block for postoperative analgesia of patients undergoing laparoscopic cholecystectomy. [PDF]
Dumanlı Özcan AT +5 more
europepmc +1 more source
Deuteration of Six‐Membered N‐Heteroarenes: Chemistry and Applications
Deuterated six‐membered N‐Heteroarenes (6NHetAr) are finding utility in an increasing repertoire of applications. Our paper comprehensively reviews synthetic approaches that have been reported for the deuteration of 6NHetAr and their fused counterparts while providing an overview of established and emerging applications for these materials.
Liju Raju +4 more
wiley +1 more source

