Results 61 to 70 of about 347,646 (292)

The effectiveness of local anesthesia of the trocar wound area in the correction of postoperative pain syndrome in colorectal oncosurgery

open access: yesВестник хирургии имени И.И. Грекова
INTRODUCTION. Severe pain syndrome is a significant complication of the postoperative period. Despite the prevalence of laparoscopic surgical interventions for colorectal cancer, there is still a lack of commonly agreed strategies to provide the most ...
A. A. Zakharenko   +4 more
doaj   +1 more source

Early synovial regulatory T cell engagement in posttraumatic osteoarthritis

open access: yesArthritis &Rheumatology, Accepted Article.
Objective Posttraumatic osteoarthritis (PTOA) develops despite restoration of joint biomechanics, suggesting that early post‐injury biological processes within the synovium shape disease trajectories. We investigated whether synovial regulatory T (Treg) cells are engaged during the early phase following joint injury and whether experimental enrichment ...
Xueyou Zhang   +5 more
wiley   +1 more source

Gabapentin as an add‐on analgesic to morphine in paediatric patients with chronic pain

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Off‐label use of gabapentin for the treatment of chronic pain in children has increased over the last decade, with multiple clinical trials evaluating its role pain management and potential opioid‐sparing effects. To date, however, these studies appear to rely on empirical evidence without further consideration of pharmacokinetic‐pharmacodynamic ...
Paul Healy   +15 more
wiley   +1 more source

Comparative evaluation of transversus abdominis plane block with transcutaneous electrical nerve stimulation for postoperative analgesia following lower segment caesarean section

open access: yesJournal of Obstetric Anaesthesia and Critical Care, 2011
Background : Pain relief after caesarean is more compelling than any other surgery. As most commonly used modalities are associated with various side-effects, a multimodal approach is recommended.
Sukhyanti Kerai   +4 more
doaj   +1 more source

A prospective, multicentre, observational cohort study of analgesia and outcome after pneumonectomy [PDF]

open access: yes, 2011
Background Meta-analysis and systematic reviews of epidural compared with paravertebral blockade analgesia techniques for thoracotomy conclude that although the analgesia is comparable, paravertebral blockade has a better short-term side-effect profile ...
Mills, R.   +44 more
core   +2 more sources

Preclinical Serial Assessment of Virtual Physiology After Implantation of a Novel Endoluminal Resorbable Fibrillated Scaffold

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background The resorbable fibrillated scaffold (RFS) is a novel electrospun, polylactide‐based endoluminal scaffold developed for peripheral arterial applications. Its porous microfibre architecture is intended to support host cell infiltration and vascular restoration.
Kotaro Miyashita   +16 more
wiley   +1 more source

Updating Clinical Practice: Improving Perioperative Pain Management for Adeno-Tonsillectomy in Children

open access: yesChildren
Background/Objective: Perioperative acute pain management in pediatric patients is essential to reduce complications. Adenoidectomy-Tonsillectomy are surgical procedures requiring pain control, and risk minimization for postoperative bleeding, nausea ...
Juan Manuel Redondo-Enríquez   +2 more
doaj   +1 more source

Tramadol Co‐Administration with Oxycodone or Hydrocodone Increases Opioid Burden without Improving Postoperative Pain Control

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Tramadol is frequently co‐prescribed with oxycodone or hydrocodone after surgery under the assumption that its dual mechanism of action provides an opioid‐sparing benefit. However, evidence supporting this practice is limited and inconsistent. We conducted a secondary analysis of the multicenter IGNITE ADOPT‐PGx pragmatic trial of patients undergoing ...
Noor A. Nahid   +302 more
wiley   +1 more source

Integration of nefopam into the postoperative multimodal analgesia protocol in orthopedic and trauma surgery - Batna university hospital [PDF]

open access: yesBatna Journal of Medical Sciences
Introduction and Objectives. Nefopam is a non-opioid central analgesic commonly employed in perioperative multimodal analgesia protocols due to its intrinsic antinociceptive properties.
Ouarda GUERZA   +2 more
doaj   +1 more source

Initiation of Gabapentin with Opioids and Risk of Respiratory Cardiovascular and Opioid‐Related Adverse Events Following Surgery for Breast Cancer

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Pain is a key determinant of quality‐of‐life following breast cancer surgery, the most common cancer operation in the United States. Gabapentinoids are frequently prescribed for pain management, yet their respiratory, cardiovascular, and opioid‐related adverse effects remain unclear.
Jyun‐Heng Lai   +12 more
wiley   +1 more source

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