Results 191 to 200 of about 51,375 (229)

Use and abuse of non-narcotic analgesics

Drug and Alcohol Dependence, 1978
The definition of abuse and dependence of non-narcotic analgesics should take into consideration the interaction of drug and personality. Usually, definitions are based on qualitative aspects of the risk-benefit ratio in the use of psychotropic drugs.
Ch. Ettlin, D. Ladewig, P.-Chr. Miest, V. Hobi, U. C. Dubach   +4 more
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Potentiation of a non-narcotic analgesic, dipyrone, by cholinomimetic drugs [PDF]

Psychopharmacologia, 1972
Dipyrone analgesia in mice was potentiated by physostigmine, neostigmine and pilocarpine. This potentiation was antagonized by atropine sulfate and atropine methyl nitrate. Tremorine and dextroamphetamine which implicate brain monoamines in their analgesic effects, were inactive, as were carbachol and nicotine.
Usha G. Kamat, Ratan J. Pradhan, Sheth Uk   +2 more
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Flunixin meglumine: a non-narcotic analgesic.

The Journal of Pharmacology and Experimental Therapeutics, 1977
The N-methyl-d-glucamine salt of flunixin (flunixin meglumine) is a potent non-narcotic analgesic agent after parenteral administration in mice, rats and monkeys. It is significantly more potent than pentazocine, meperidine and codeine in the rat yeast paw test after subcutaneous administration in saline.
V B, Ciofalo, M B, Latranyi, J B, Patel, R I, Taber   +3 more
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Metabolism of the non-narcotic analgesic, Wy-535

Biochemical Pharmacology, 1965
Abstract Hexahydro-1,3-dimethyl-4-phenylazepine-4-14C-carboxylic acid, ethyl ester (Wy-535), was administered to dogs and rats both orally and intramuscularly. Tissue levels were determined in the rat, and plasma levels as well as urinary and fecal excretion rates were determined in both species.
R.A. Corradino, Sidney S. Walkenstein, Robert Wiser, Cathryn H. Gudmundsen   +3 more
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Abuse of Non-Narcotic Analgesics

1977
After reports had first been published from Switzerland referring to the abuse of antipyretic analgesics containing phenacetin (Kielholz, 1954; Horrisberger et al., 1958; Battegay, 1958) and to the possibility of a causal connection between such abuse and chronic renal diseases (Spuhler and Zollinger, 1963), numerous authors subsequently drew attention
P. Kielholz, D. Ladewig
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4 Promising non-narcotic analgesic techniques for labour

Baillière's Clinical Obstetrics and Gynaecology, 1998
Epidural analgesia and spinal analgesia are the most effective techniques for relieving labour pain. Basically, local anaesthetics (i.e. bupivacaine) and opioids (i.e. fentanyl or sufentanil), especially when combined, produce excellent analgesia with minimal motor blockade.
Frédéric J. Mercier, Dan Benhamou
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The effect of non-steroidal anti-inflammatory drugs and other commonly used non-narcotic analgesics on blood pressure level in adults.

Journal of Hypertension, 2006
This review explores the blood pressure effects of three non-narcotic analgesics: non-selective non-steroidal anti-inflammatory drugs (NSAID), paracetamol and aspirin.
Sarah Wilson, N. Poulter
semanticscholar   +1 more source

Blockade by l-lysine of non-narcotic analgesics.

The Journal of Pharmacology and Experimental Therapeutics, 1980
The antinociceptive effects of the non-narcotic analgesics clonixin, flunixin, acetylsalicylic acid, aminopyrine and phenylbutazone in the yeast paw test were blocked by l-lysine. Blockade occurred at doses of l-lysine which did not affect pain threshold. The site(s) or mechanism of action of blockade could not be determined with certainty.
L C, Iorio, M, Latranyi, E, Heath, A, Barnett   +3 more
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Pharmacokinetics of a non-narcotic analgesic, DA-5018, in rats

Biopharmaceutics & Drug Disposition, 1998
The pharmacokinetics of a non-narcotic analgesic, DA-5018, were compared after single intravenous (i.v.), subcutaneous (s.c.), and oral administrations, and after multiple (seven consecutive days) s.c. administration to rats. After i.v. administration of DA-5018, 1, 2, and 5 mg kg-1, the pharmacokinetic parameters of DA-5018 were independent of the ...
Myung Gyoon Lee, Jong J. Lee, Sang D. Lee, Junnick Yang, Hyun J. Shim, Won B. Kim, So H. Kim   +6 more
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Tazadolene: A centrally‐acting, non‐narcotic analgesic [PDF]

Drug Development Research, 1988
AbstractIntravenous tazadolene elevated the threshold stimulus for rabbits to respond to electrical tooth‐pulp stimulation. Systemic tazadolene also increased the latency for mice to lick their paws in the hot‐plate analgesic test. However, tazadolene did not alter the mouse tail flick, a spinal reflex most sensitive to analgesics acting at spinal ...
openaire   +1 more source