Results 211 to 220 of about 283,091 (360)

Trametinib in Adults with Neurofibromatosis Type 1‐Related Symptomatic Plexiform Neurofibromas

open access: yesAnnals of Neurology, EarlyView.
Objective Mitogen‐activated protein kinase kinase inhibitors have shown promising results in treatment of plexiform neurofibromas in neurofibromatosis type 1 patients, but data in adults are limited. The aim of this phase 2 study was to investigate the efficacy and safety of trametinib in adults with neurofibromatosis type 1.
D. Christine Noordhoek   +7 more
wiley   +1 more source

Opioid analgesics for chronic noncancer pain in patients prescribed opioid agonist therapy or with opioid use disorder: A systematic review. [PDF]

open access: yesCan J Pain
Ashoorion V   +9 more
europepmc   +1 more source

Identification of New KCNT1‐Epilepsy Drugs by In Silico, Cell, and Drosophila Modeling

open access: yesAnnals of Neurology, EarlyView.
Objective Hyperactive KCNT1 potassium channels, caused by gain‐of‐function mutations, are associated with a range of epilepsy disorders. Patients typically experience drug‐resistant seizures and, in cases with infantile onset, developmental regression can follow.
Michael G. Ricos   +9 more
wiley   +1 more source

Analgesic Action of Dialkylaminoacylamino Derivatives. I

open access: bronze, 1953
Kikuo Ogiu   +5 more
openalex   +2 more sources

Everolimus‐Coated Laser‐Cut Self‐Expandable Metallic Stent Suppresses Stent‐Induced Tissue Hyperplasia in a Rat Gastric Outlet

open access: yesAdvanced NanoBiomed Research, EarlyView.
Everolimus‐coated laser‐cut self‐expandable metallic stents suppress stent‐induced tissue hyperplasia in the gastric outlet by reducing inflammation, fibrosis, and smooth muscle proliferation. Herein, we demonstrate the mechanical stability, sustained drug release, and histological benefits in a rat gastric outlet model, suggesting potential for ...
Yubeen Park   +10 more
wiley   +1 more source

Synthesis of Analgesics. II

open access: bronze, 1954
Torizo Takahashi, Mikio Hori
openalex   +2 more sources

Home - About - Disclaimer - Privacy