Results 21 to 30 of about 23,449 (261)

Doubling-resolution analog-to-digital conversion based on PIC18F45K80

The Journal of Engineering, 2014
Aiming at the analog signal being converted into the digital with a higher precision, a method to improve the analog-to-digital converter (ADC) resolution is proposed and described. Based on the microcomputer PIC18F45K80 in which the internal ADC modules
Yueyang Yuan, Chongchang Yang
doaj   +1 more source

Features of the implementation of a digital-to-analog conversion based on pulse-width modulation and an RC circuit

Известия Томского политехнического университета: Промышленная кибернетика
In scientific, educational, and technical applications, smooth voltage regulation over a specific range is often required. Most modern devices are controlled by digital microcontrollers, necessitating specialized devices – digital-to-analog conversion ...
Kirill A. Volobuev, Violetta M. Moskaleva, Igor V. Trubin, Vitaly G. Trubin   +3 more
doaj   +1 more source

Breakthroughs in Photonics 2012: Generation of Modulated Optical Signals for Optical Fiber Communications

IEEE Photonics Journal, 2013
Recent advances in transmitters for optical fiber communications that exploit the powerful capabilities of digital signal processing and digital-to-analog conversion are reviewed.
J. C. Cartledge, A. S. Karar
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

The new CAS-DIS digital ionosonde

Annals of Geophysics, 2013
A high quality digital ionosonde called the Chinese Academy of Sciences digital ionosonde (CAS-DIS) has been developed for investigations of the ionosphere.
Wang Shun, Chen Ziwei, Zhang Feng, Fang Guangyou   +3 more
doaj   +1 more source

Analog Convolutional Operator Circuit for Low-Power Mixed-Signal CNN Processing Chip

Sensors, 2023
In this paper, we propose a compact and low-power mixed-signal approach to implementing convolutional operators that are often responsible for most of the chip area and power consumption of Convolutional Neural Network (CNN) processing chips.
Malik Summair Asghar, Saad Arslan, HyungWon Kim   +2 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source