Results 21 to 30 of about 23,424 (252)

On the issue of numerical transformation of seismological signal

Геофизический журнал, 2012
This article is devoted to conversion of seismic analog signal to digital code. The conversion is done by means of microprocessor instead of digital signal processor. This makes the data handling cheaper retaining its efficiency.
I. Yu. Mikhaylik, K. V. Petrenko
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Dickson-Charge-Pump-Based Voltage-to-Time Conversion for Time-Based ADCs in 28-nm CMOS

IEEE Open Journal of Circuits and Systems, 2021
This article demonstrates a digitally friendly time-based analog-to-digital converter (ADC) exploiting Dickson charge-pump (CP) as part of a voltage-to-time conversion (VTC) implemented in 28-nm CMOS. In the proposed technique, the Dickson CP generates a
Ali Esmailiyan, Jianglin Du, Teerachot Siriburanon, Filippo Schembari, Robert Bogdan Staszewski   +4 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

On Full-Duplex Radios With Modulo-ADCs

IEEE Open Journal of the Communications Society, 2021
Wireless full-duplex (FD) transceivers have become more commonplace in the recent years, enabled by improvements in hardware as well as in signal processing algorithms dedicated to self-interference (SI) mitigation.
Luis G. Ordonez, Paul Ferrand, Melissa Duarte, Maxime Guillaud, Ganghua Yang   +4 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Beyond Sole Parametric Optimization Design Regimes: Understanding and Advancing the Frontiers of High-Speed ADCs

IEEE Open Journal of the Solid-State Circuits Society
Driven by relentless demands for expeditious data acquisition in modern communication systems, radar, and instrumentation, Nyquist analog-to-digital converters (ADCs) have emerged as critical components due to their ability to direct sample and digitize ...
Chi-Hang Chan
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Features of the implementation of a digital-to-analog conversion based on pulse-width modulation and an RC circuit

Известия Томского политехнического университета: Промышленная кибернетика
In scientific, educational, and technical applications, smooth voltage regulation over a specific range is often required. Most modern devices are controlled by digital microcontrollers, necessitating specialized devices – digital-to-analog conversion ...
Kirill A. Volobuev, Violetta M. Moskaleva, Igor V. Trubin, Vitaly G. Trubin   +3 more
doaj   +1 more source