Results 61 to 70 of about 618,182 (326)

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang, Huiying Wang, Zhizheng Zhuo, Ai Guo, Ke Lv, Decai Tian, Chao Chai, Yunyun Duan, Shuang Xia   +8 more
wiley   +1 more source

Experimental Study on a 4-b Serial Optical Digital to Analog Convertor

IEEE Photonics Journal, 2018
Photonic techniques have potential to overcome the limitations of electronic digital-to-analog conversion. A serial optical DAC, using fiber dispersion with optical weighted wavelength multiplexing, is proposed and demonstrated.
Tianhang Zhang, Qi Qiu, Zhiqiang Fan, Jun Su, Mingzhu Xu   +4 more
doaj   +1 more source

Investigation of critical slowing down in a bistable S-SEED

, 2003
A simulation of S-SEED switching based upon experimental data is developed that includes the effect of critical slowing down. The simulation's accuracy is demonstrated by close agreement with the results from experimental S-SEED switching. The simulation
Marwood, W., Atanackovic, P., Munch, J., Grant, K., Clare, B., Corbett, K.   +5 more
core   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

An Improved Linearization Circuit Used for Optical Rotary Encoders

Measurement Science Review, 2017
Optical rotary encoders generate nonlinear sine and cosine signals in response to a change of angular position that is being measured. Due to the nonlinear shape of encoder output signals, encoder sensitivity to very small changes of angular position is ...
Jovanović Jelena, Denić Dragan, Jovanović Uglješa   +2 more
doaj   +1 more source

Advancing Age Modulates Associations Between Cognitive Impairment and Brain Volumes in Early MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Cognitive impairment is common in multiple sclerosis (MS), but manifestations following the first demyelinating event are relatively unexplored. We investigated cross‐sectional associations between magnetic resonance imaging (MRI)–derived brain volumes and the presence of cognitive impairment outcomes five years after the first ...
Piriyankan Ananthavarathan, Marco Pitteri, Michael Foster, Sara Collorone, Sara Salama, Elisa Colato, Ferran Prados, Baris Kanber, Marios Yiannakas, Claudia A. M. Gandini Wheeler‐Kingshott, Indran Davagnanam, Frederik Barkhof, Declan Chard, Olga Ciccarelli, Ahmed Toosy   +14 more
wiley   +1 more source

Scalable Photonic Digital-to-Analog Converters

Photonics
This work introduces a novel architecture for implementing a parallel coherent photonic digital-to-analog converter (PDAC), designed to transform parallel digital electrical signals into corresponding analog optical output, convertible to analog ...
Md Mahadi Masnad, S. Mohammad Reza Safaee, Najla Najeeb, Kaveh Rahbardar Mojaver, Mohamed Fouda, Emanuel Peinke, Odile Liboiron-Ladouceur   +6 more
doaj   +1 more source

Artificial Intelligence in Systemic Sclerosis: Clinical Applications, Challenges, and Future Directions

Arthritis Care &Research, EarlyView.
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos, José Miguel Sequí‐Sabater, Diego Benavent   +2 more
wiley   +1 more source

Optical coding scheme using optical interconnection for high sampling rate and high resolution photonic analog-to-digital conversion.

Optics Express, 2007
We propose and demonstrate an optical coding scheme using optical interconnection for a photonic analog-to-digital conversion. It allows us to convert a multi-power level signal into a multiple-bit binary code so as to detect it in a bit-parallel format ...
T. Nishitani, T. Konishi, K. Itoh
semanticscholar   +1 more source

All photonic analogue to digital and digital to analogue conversion techniques for digital radio over fibre system applications

, 2011
Copyright @ 2011 IEEEWideband electronic analogue to digital conversion (ADC) systems have critical problems encountered in high-frequency broadband communication systems that the recent electronic ADCs (EADC) have experienced those such as uncertainty ...
Mehdi Fakhraie, S, Nilavalan, R, Abdollahi, SR, Al-Raweshidy, H   +3 more
core