Results 161 to 170 of about 1,420,454 (298)

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Evaluation of model accuracy and implant analog position in stone and additively manufactured models with different resin viscosities. [PDF]

BMC Oral Health
Çınar G, Demir N, Güven ME.
europepmc   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen, Jia‐Ci Jhang, Chun‐Yi Peng, Quốc Cường Nguyễn, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin   +6 more
wiley   +1 more source

Pruning random resistive memory for optimizing analog AI. [PDF]

Nat Commun
Li Y, Wang S, Zhao Y, Wang S, Wang B, Zhang W, He Y, Lin N, Cui B, Chen X, Zhang S, Jiang H, Lin P, Zhang X, Zhang F, Qi X, Wang Z, Xu X, Shang D, Liu Q, Wang H, Cheng KT, Liu M.   +22 more
europepmc   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Quantum-inspired superposition and nonseparable states of reconfigurable metasurfaces in classical systems. [PDF]

Nat Commun
Chen L, You JW, Ma Q, Su JL, Qin SL, Peng QC, Xiao Q, Cui TJ.   +7 more
europepmc   +1 more source

Analog und Analog

, 2004
openaire   +2 more sources

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Evaluation of an event-driven 3FI ASIC for spectroscopic X-ray detection with synchrotron radiation. [PDF]

J Synchrotron Radiat
Maj P, Deptuch GW, Gorni DS, Pinaroli G, Carini GA, Siddons DP, Tappero R, Mandal S, Pinelli D, Kersten T, St John N, Rumaiz AK, Kuczewski A.   +12 more
europepmc   +1 more source

Analogy [PDF]

Clinical Nursing Research, 2000
openaire   +2 more sources