Results 231 to 240 of about 1,420,454 (298)

Effect of Foot Orthoses on Midfoot Pain and the Volume of Bone Marrow Lesions in the Midfoot: A Randomized Mechanism of Action Study

Arthritis Care &Research, EarlyView.
Objective Foot orthoses are thought to improve pain by potentially modifying internal mechanical forces. To test this, we explored whether foot orthoses can modify patterns of bone marrow lesions (BMLs) in people with midfoot pain. Methods Forty‐two people were recruited with midfoot pain, and magnetic resonance imaging–confirmed midfoot BMLs ...
Jill Halstead, Anne‐Maree Keenan, Philip G. Conaghan, Dennis McGonagle, Anthony C. Redmond   +4 more
wiley   +1 more source

SynTwins: a retrosynthesis-guided framework for synthesizable molecular analog generation. [PDF]

Chem Sci
Chen S, Nam G, Aspuru-Guzik A, Jung Y.
europepmc   +1 more source

Financial Distress and Its Determinants in Rheumatoid Arthritis

Arthritis Care &Research, EarlyView.
Objective To quantify the degree of financial distress and identify its determinants in adults with rheumatoid arthritis (RA) given the frequent prolonged use of expensive disease‐modifying therapies. Methods We identified adults enrolled in the FORWARD databank with either RA or noninflammatory musculoskeletal disease (NIMSKD) completing the ...
Amber Brown Keebler, Yunju Im, Sofia Pedro, Ted R. Mikuls, Edward S. Peters, Kaleb Michaud   +5 more
wiley   +1 more source

A Streamlined In Vitro mRNA Production Evaluation for mRNA-Based Vaccines and Therapeutics. [PDF]

Methods Protoc
Madia V, Minesso S, Franceschi V, Donofrio G.   +3 more
europepmc   +1 more source

Sarilumab in Polyarticular‐Course Juvenile Idiopathic Arthritis: Dose‐Finding and One‐Year Analysis of a Phase 2b, Open‐Label, Multicenter Study

Arthritis Care &Research, Accepted Article.
Objective This study assessed sarilumab in treating patients with polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods This phase 2b, open‐label study (NCT02776735) consisted of three sequential parts (each with a core‐treatment and extension‐phase). During part 1, three doses were assessed in two weight groups (Group A/B: ≥30–60 kg/≥10–<
Fabrizio De Benedetti, Inmaculada C. Penadés, Irina Nikishina, Ivan Foeldvari, Alberto J. Spindler, Anna Kozlova, Nadina Rubio‐Pérez, Pierre Quartier, Zbigniew Żuber, Raul Barria, Daniel Clemente, Gabriel V. Cornejo, Katherine Marzan, Nancy Liu, Christine Xu, Stephen DiMartino, Angeliki Giannelou, Fei Cao‐Ghoul, Bolanle Akinlade, Lydie Baret‐Cormel   +19 more
wiley   +1 more source

From Bench to Bioactivity: An Integrated Medicinal Development Based on Kinetic and Simulation Assessment of Pyrazolone-Oxadiazole Coupled Benzamide as Promising Inhibitors of Diabetes Mellitus. [PDF]

Pharmaceuticals (Basel)
Khowdiary MM, Felemban S.
europepmc   +1 more source

Design of a compact digital to analog converter with optical Kerr effect. [PDF]

Sci Rep
Parandin F, Jomour M, Karami B.
europepmc   +1 more source

Design and Simulation of a Portable Five-Lead ECG Monitoring Device With Adaptive Filtering for Continuous Remote Cardiac Assessment. [PDF]

Cureus
Rrmoku D.
europepmc   +1 more source

Fe²⁺ disproportionation within iron-rich alkaline vent analogues reveals proto-bioenergetic systems. [PDF]

Nat Commun
Truong C, Gaudu N, Farr O, Clouet A, Ferry D, Guyot F, Ona-Nguema G, Ruby C, Nitschke W, Grauby O, Duval S.   +10 more
europepmc   +1 more source

Portable Multichannel Measurement System for Real-Time Microplastics Assessment Using Microwave Sensors. [PDF]

Sensors (Basel)
Barrancos A, Rosinha D, Assis J, Rosado LS.   +3 more
europepmc   +1 more source