Results 201 to 210 of about 298,951 (296)

Parallel 3D Bioprinting on SLIPS‐Microarrays

open access: yesAdvanced Functional Materials, EarlyView.
This work introduces the first truly parallel 3D bioprinting method, enabling both the simultaneous fabrication of hundreds of cell laden hydrogel 3D structures and their HTS in individual liquid compartments. By integrating Digital Light Processing (DLP) stereolithography with functional micropatterns, the platform decouples printing time from array ...
Julius von Padberg   +3 more
wiley   +1 more source

Light Activated Induction of Cuproptosis in Resistant Cancer Cells Using Polymeric BODIPY Nanoparticles for Photoactivated Chemotherapy

open access: yesAdvanced Functional Materials, EarlyView.
This article presents a photo‐responsive nanoparticle platform that precisely triggers copper‐dependent cuproptotic cell death in (drug‐resistant) cancer cells. The system remains stable and inactive in the dark but releases cytotoxic species upon red‐light irradiation, achieving potent activity in drug‐resistant breast cancer cells.
Ricarda Zimmermann   +2 more
wiley   +1 more source

Microenvironmental Reprogramming by 3D Anisotropic Cardiac Extracellular Matrix Induces Nuclear Remodeling and Epigenetic Maturation of Chemically Induced Cardiomyocytes

open access: yesAdvanced Functional Materials, EarlyView.
A 3D anisotropic hydrogel derived from heart extracellular matrix guides cytoskeletal alignment and nuclear remodeling in reprogrammed cardiomyocyte‐like cells. This study reveals how matrix alignment modulates nuclear envelope dynamics and chromatin state, triggering transcriptional and functional maturation.
Seung Ju Seo   +7 more
wiley   +1 more source

Photon Avalanching Nanoparticles: The Next Generation of Upconverting Nanomaterials?

open access: yesAdvanced Functional Materials, EarlyView.
This Perspective outlines the mechanistic foundations that enable photon‐avalanche (PA) behavior in lanthanide nanomaterials and contrasts them with emerging application spaces and forward‐looking design strategies. By bridging threshold engineering, energy‐transfer dynamics, and materials engineering, we provide a coherent roadmap for advancing the ...
Kimoon Lee   +7 more
wiley   +1 more source

New Analogs of the Compstatin Family of Clinical Complement Inhibitors with Low Picomolar Target Affinity. [PDF]

open access: yesJ Med Chem
Vogt SA   +12 more
europepmc   +1 more source

Meniscus Pixel Printing for Contact‐Lens Vision Sensing and Robotic Control

open access: yesAdvanced Functional Materials, EarlyView.
A visual‐sensing contact lens is enabled by meniscus pixel printing (MPP), which rapidly patterns a 200 µm perovskite photodetector pixel in 1 s without masks, vacuum processing, or bulky equipment. A deep‐learning‐based super‐resolution reconstructs sparse on‐lens signals into 80 × 80 high‐resolution visual information, while AI‐driven eye‐tracking ...
Byung‐Hoon Gong   +7 more
wiley   +1 more source

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