Results 91 to 100 of about 163,099 (316)

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Low-power low-noise analog circuits for on-focal-plane signal processing of infrared sensors [PDF]

open access: green, 1993
Bedabrata Pain   +4 more
openalex   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Three Microwave Frequency Dividers Using Current Source/Sink and Modified Current Source Inverters

open access: yesActive and Passive Electronic Components, 2013
In a preceding paper Carlos E. Saavedra, 2005, established that frequency division can be achieved with the use of inverter rings and transmission gates.
Gautham S. Harinarayan   +1 more
doaj   +1 more source

Multi‐omic profiling of squamous cell lung cancer identifies metabolites and related genes associated with squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Using multi‐omic characterization, we aimed to identify key regulators specific to squamous cell lung carcinoma (SqCC). SqCC‐specific differentially expressed genes were integrated with metabolics data. High expression of the creatine transporter SLC6A8, along with elevated creatine levels, appeared to be a distinct metabolic feature of SqCC.
Johan Staaf   +10 more
wiley   +1 more source

A Fast Startup 38.4-MHz Crystal Oscillator Achieving 99-nJ Startup Energy With Adaptive Chirping

open access: yesIEEE Access
Shortening the startup time of a crystal oscillator is critical in improving the energy efficiency of the Internet of Things (IoT) sensor nodes. This article presents an investigative study on the application of adaptive chirping using zero-phase cross ...
Abdolraouf Rahmani   +6 more
doaj   +1 more source

The equivalence of digital and analog signal processing

open access: yesInformation and Control, 1965
Summary: A specific isomorphism is constructed via the transform domains between the analog signal space \(L^2(-\infty, \infty)\) and the digital signal space \(l_2\). It is then shown that the class of linear time-invariant realizable filters is invariant under this isomorphism, thus demonstrating that the theories of processing signals with such ...
openaire   +2 more sources

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

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