Results 91 to 100 of about 585,344 (349)

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Inexpensive, stable circuit measures heart rate [PDF]

open access: yes, 1965
Inexpensive transistorized circuit provides reliable analog indications of heart rate in response to preamplified electrocardiograph signal applied to its ...
Vick, H. A.
core   +1 more source

Online Codes for Analog Signals

open access: yesIEEE Transactions on Information Theory, 2019
This paper revisits a classical scenario in communication theory: a waveform sampled at regular intervals is to be encoded so as to minimize distortion in its reconstruction, despite noise. This transformation must be online (causal), to enable real-time signaling; and should use no more power than the original signal. The noise model we consider is an
Leonard J. Schulman, Piyush Srivastava
openaire   +3 more sources

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Random Filters for Compressive Sampling [PDF]

open access: yes, 2007
This paper discusses random filtering, a recently proposed method for directly acquiring a compressed version of a digital signal. The technique is based on convolution of the signal with a fixed FIR filter having random taps, followed by downsampling ...
Tropp, Joel A.
core  

Minimum BER Precoding in 1-Bit Massive MIMO Systems

open access: yes, 2017
1-bit digital-to-analog (DACs) and analog-to-digital converters (ADCs) are gaining more interest in massive MIMO systems for economical and computational efficiency.
Jedda, Hela   +2 more
core   +1 more source

Drug screening on digital microfluidics for cancer precision medicine

open access: yesNature Communications
Drug screening based on in-vitro primary tumor cell culture has demonstrated potential in personalized cancer diagnosis. However, the limited number of tumor cells, especially from patients with early stage cancer, has hindered the widespread application
Jiao Zhai   +21 more
doaj   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Circuit measures hysteresis loop areas at 30 Hz [PDF]

open access: yes, 1967
Analog circuit measures hysteresis loop areas as a function of time during fatigue testing of specimens subjected to sinusoidal tension-compression stresses at a frequency of Hz.
Hoffman, C., Spilo, D.
core   +1 more source

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