Results 41 to 50 of about 163,099 (316)

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

FEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu, Huseyn Babayev, Ismail Ogulur, Sena Ardicli, Yagiz Pat, Duygu Yazici, Bingjie Zhao, Lihong Chang, Xiaoqing Liu, Paolo D'Avino, Manru Li, Ceren Biçer, Fatma Hacer Kurtoğlu Babayev, Raja Dhir, Kari C. Nadeau, Marie‐Charlotte Brüggen, Mubeccel Akdis, Cezmi A. Akdis   +17 more
wiley   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

Experimental Verifications of Low Frequency Path Gain ( $PG$ ) Channel Modeling for Implantable Medical Device (IMD)

IEEE Access, 2019
With the development of microelectronics and sensor technologies, implantable electronic devices are employed in many applications. These devices are distributed on or in the human bodies and are used to transmit signals wirelessly to external equipment.
Shuang Zhang, Sio-Hang Pun, Peng Un Mak, Yu Ping Qin, Yi He Liu, Yue Ming Gao, Mang I Vai   +6 more
doaj   +1 more source

A Fully-Integrated CMOS Dual-Band RF Energy Harvesting Front-End Employing Adaptive Frequency Selection

IEEE Access, 2023
This paper proposes a fully-integrated dual-band CMOS RF energy harvesting (RFEH) front-end with an adaptive frequency selector that can select between two harvesting frequencies of 1.9 GHz and 2.4 GHz. The RFEH front end includes two pairs of on-chip LC
Wen Xun Lian, Harikrishnan Ramiah, Gabriel Chong, Kishore Kumar Pakkirisami Churchill, Nai Shyan Lai, Saad Mekhilef, Yong Chen, Pui-In Mak, Rui P. Martins   +8 more
doaj   +1 more source

Almost lossless analog signal separation [PDF]

2013 IEEE International Symposium on Information Theory, 2013
To be presented at IEEE Int. Symp. Inf.
Erwin Riegler, Helmut Bölcskei, David Stotz   +2 more
openaire   +4 more sources

Thermostable neutral metalloprotease from Geobacillus sp. EA1 does not share thermolysin's preference for substrates with leucine at the P1′ position

FEBS Letters, EarlyView.
Knowing how proteases recognise preferred substrates facilitates matching proteases to applications. The S1′ pocket of protease EA1 directs cleavage to the N‐terminal side of hydrophobic residues, particularly leucine. The S1′ pocket of thermolysin differs from EA's at only one position (leucine in place of phenylalanine), which decreases cleavage ...
Grant R. Broomfield, Torsten Kleffmann, David J. Saul, Sigurd M. Wilbanks   +3 more
wiley   +1 more source

Design and Implementation of Hybrid DC-DC Converter: A Review

IEEE Access, 2023
The advancement in Power Management Integrated Circuit (PMIC) has driven the dc-dc conversion technology into a System-on-Chip (SoC) solutions, leveraging CMOS technology scaling from 180nm to 22nm and on-chip passive element integration.
Teck Seong Chang, Harikrishnan Ramiah, Yang Jiang, Chee Cheow Lim, Nai Shyan Lai, Pui-In Mak, Rui P. Martins   +6 more
doaj   +1 more source

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

FEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan, Victoria Scarpelli, Marten Exterkate   +2 more
wiley   +1 more source

Wideband Continuous-Time MASH ADCs: Principles, Challenges, and Prospects

IEEE Open Journal of the Solid-State Circuits Society
Continuous-time (CT) delta-sigma modulator (DSM) is a popular choice for its inherent aliasing and resistive input impedance characteristics. With the increased demands for wide-bandwidth (BW) and high-dynamic range (DR), multistage noise shaping (MASH ...
Ke Li, Liang Qi, Mingqiang Guo, Rui P. Martins, Sai-Weng Sin   +4 more
doaj   +1 more source

Structural dynamics of the plant hormone receptor ETR1 in a native‐like membrane environment

FEBS Letters, EarlyView.
The present study unveils the structural and signaling dynamics of ETR1, a key plant ethylene receptor. Using an optimized nanodisc system and solution NMR, we captured full‐length ETR1 in a native‐like membrane environment. Our findings reveal dynamic domain uncoupling and Cu(I)‐induced rigidification, providing the first evidence of metal‐triggered ...
Moritz Lemke, Nils Alexander Lakomek, Georg Groth   +2 more
wiley   +1 more source