Results 81 to 90 of about 580,719 (297)
Drug screening of cancer cell lines and human primary tumors using droplet microfluidics
Scientific Reports, 2017 Precision Medicine in Oncology requires tailoring of therapeutic strategies to individual cancer patients. Due to the limited quantity of tumor samples, this proves to be difficult, especially for early stage cancer patients whose tumors are small.
Ada Hang-Heng Wong +11 more
doaj +1 more source
Analog and Mixed Signal Verification [PDF]
, 2008 More and more electronic systems have components that are not purely digital. Verification of such systems is a much less developed discipline than the digital equivalents and the application of formal (mathematically complete) techniques is a nascent ...
Jones, K.
core
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Random Filters for Compressive Sampling [PDF]
, 2007 This paper discusses random filtering, a recently proposed method for directly acquiring a compressed version of a digital signal. The technique is based on convolution of the signal with a fixed FIR filter having random taps, followed by downsampling ...
Tropp, Joel A.
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Xampling: Signal Acquisition and Processing in Union of Subspaces
, 2011 We introduce Xampling, a unified framework for signal acquisition and processing of signals in a union of subspaces. The main functions of this framework are two.
Eldar, Yonina C. +2 more
core +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Advanced ScienceDrug screening of primary tumor cells directly assesses the drug efficacy on specific tumors, promoting personalized cancer treatment. The application of a microfluidic platform has realized drug screening using a limited amount of biopsy samples for ...
Wenhao Hui +13 more
doaj +1 more source
Isolated transfer of analog signals [PDF]
, 1974 Technique transfers analog signal levels across high isolation boundary without circuit performance being affected by magnetizing reactance or leakage inductance.
Bezdek, T.
core +1 more source
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Circuit measures hysteresis loop areas at 30 Hz [PDF]
, 1967 Analog circuit measures hysteresis loop areas as a function of time during fatigue testing of specimens subjected to sinusoidal tension-compression stresses at a frequency of Hz.
Hoffman, C., Spilo, D.
core +1 more source