Results 21 to 30 of about 179,740 (256)
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Nonequilibrium valley polarization in graphene nanoconstrictions
, 2007 We recently shown, using tight-binding calculations, that nonequilibrium valley polarization can be realized in graphene, when the current is injected through "valley filter": a ballistic point contact with zigzag edges.
Akhmerov +28 more
core +1 more source
Developing and evaluating a hybrid wind instrument [PDF]
, 2014 A hybrid wind instrument generates self-sustained sounds via a real-time interaction between a computed excitation model (such as the physical model of human lips interacting with a mouthpiece) and a real acoustic resonator.
Buys, Kurijn, Laney, Robin, Sharp, David
core +2 more sources
Charge-coupled-device analogue matched filters
Electronics Letters, 1972 Charge-coupled-device shift registers are used to construct filters matched to both a 13-chip Barker-coded p-n sequence and a chirp signal with a time-bandwidth product of 10. The letter describes the design and fabrication of the devices, and presents preliminary operational characteristics of the filters.
D.R. Collins +3 more
openaire +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Realization of Analog Wavelet Filter using Hybrid Genetic Algorithm for On-line Epileptic Event Detection [PDF]
, 2020 © 2020 The Author(s). This open access work is licensed under a Creative Commons Attribution 4.0 License. For more information, see http://creativecommons.org/licenses/by/4.0/.As the evolution of traditional electroencephalogram (EEG) monitoring unit for
He, Yigang +4 more
core +2 more sources
Monolithic, programmable analogue c.c.d. transversal filter
Electronics Letters, 1977 A 64-point monolithic, fully programmable analogue c.c.d. transversal filter has been produced. The design principles and limitations of this approach are discussed, and results are presented for the filter acting as a chirp-waveform correlator and for other filtering functions.
P.B. Denyer, J.W. Arthur, J. Mavor
openaire +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source