Results 51 to 60 of about 179,740 (256)

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

open access: yesMolecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

On comparison of constrained and unconstrained evolutions in analogue electronics on the example of “LC” low-pass filters [PDF]

open access: yes, 2006
The Evolutionary Electronics refers to the design method of electronic circuits with the help of Evolutionary Algorithms. Over the years huge experience has been accumulated and tremendous results have been achieved in this field.
Kalganova, T, Sapargaliyev, Y
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Phase Transitions in Nonlinear Filtering

open access: yes, 2014
It has been established under very general conditions that the ergodic properties of Markov processes are inherited by their conditional distributions given partial information.
Rebeschini, Patrick, van Handel, Ramon
core   +1 more source

Fibre segment interferometry using code-division multiplexed optical signal processing for strain sensing applications [PDF]

open access: yes, 2013
A novel optical signal processing scheme for multiplexing fibre segment interferometers is proposed. The continuous-wave, homodyne technique combines code-division multiplexing with single-sideband modulation.
Charrett, Thomas O. H.   +2 more
core   +1 more source

Wave analogue filters using switched-current techniques

open access: yesElectronics Letters, 1991
A new approach to sampled-data filter realisation based on switched-current techniques is presented. The new method relies on the wave-digital filter concept. A methodology to obtain current-wave analogue filters and some preliminary results are explained. The simplicity and correctness of the approach are encouraging for future work.
A. Rueda, A. Yüfera, J.L. Huertas
openaire   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Digitizing signals - a short tutorial guide

open access: yes, 2004
Converting the analogue signal, as captured from a patient, into digital format is known as digitizing, or analogue to digital conversion. This is a vital first step in for digital signal processing.
De Stefano, A., Simpson, D.M.
core  

High-performance digitally programmable analogue transversal filter

open access: yesElectronics Letters, 1978
An electrically programmable transversal filter is presented, based on a tapped analogue delay line. The experimental results presented here highlight the large dynamic range capability of the filter structure. The approach is highly suitable for monolithic implementation using standard c.t.d. technology.
D. Roy, P. Menard
openaire   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

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