Results 91 to 100 of about 1,342,850 (388)

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

open access: yesFEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić   +3 more
wiley   +1 more source

Bulgakov and Milbank: towards a critique of secular reason [PDF]

open access: yesВестник Свято-Филаретовского института
The article is dedicated to the comparative analysis of the phenomenon of secularism in the works of the Russian philosopher and theologian Fr. Sergius Bulgakov and the English theologian John Milbank.
Syundyukov Nikita K.
doaj   +1 more source

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

open access: yesFEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul   +3 more
wiley   +1 more source

Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe

open access: yesFEBS Open Bio, EarlyView.
Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley   +1 more source

Exemple historique, comparaison, analogie, métaphore : sont-ils interchangeables ?

open access: yesArgumentation et Analyse du Discours, 2016
Critical meta-discourses dealing with the notion of historical example often allow us to observe an unexpected phenomenon: in the heat of their demonstration, both scholars and lay persons do not distinguish between example, comparison, analogy or ...
Roselyne Koren
doaj   +1 more source

Symmetries and Paraparticles as a Motivation for Structuralism [PDF]

open access: yes, 2009
This paper develops an analogy proposed by Stachel between general relativity (GR) and quantum mechanics (QM) as regards permutation invariance. Our main idea is to overcome Pooley's criticism of the analogy by appeal to paraparticles.
Butterfield, Jeremy, Caulton, Adam
core  

Analogy Mining for Specific Design Needs

open access: yes, 2017
Finding analogical inspirations in distant domains is a powerful way of solving problems. However, as the number of inspirations that could be matched and the dimensions on which that matching could occur grow, it becomes challenging for designers to ...
Bahdanau Dzmitry   +11 more
core   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

open access: yesFEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori   +8 more
wiley   +1 more source

Riding Horse Harness (Based on Materials from the Chulkovo Burial Ground)

open access: yesПоволжская археология, 2013
The items of riding horse harness (bits with psalia, stirrups, buckles, decorations of bridles) are analyzed in the article on the basis of the materials from the Chulkovo (Murom) burial ground site of the 8th-10th centuries, located on right bank of the
Grishakov Valeriy V. , Sedyshev Oleg V
doaj   +1 more source

Analogical insight: toward unifying categorization and analogy [PDF]

open access: yesCognitive Processing, 2010
The purpose of this paper is to present two kinds of analogical representational change, both occurring early in the analogy-making process, and then, using these two kinds of change, to present a model unifying one sort of analogy-making and categorization.
openaire   +2 more sources

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