Results 101 to 110 of about 1,342,850 (388)
FEBS Open Bio, EarlyView.Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu +5 more
wiley +1 more source
An information theory for preferences
, 2003 Recent literature in the last Maximum Entropy workshop introduced an analogy between cumulative probability distributions and normalized utility functions. Based on this analogy, a utility density function can de defined as the derivative of a normalized
Abbas, Ali E.
core +1 more source
FEBS Open Bio, EarlyView.KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani +6 more
wiley +1 more source
, 2014 Bio-inspired design and the broader field of design-by-analogy have been the basis of numerous innovative designs throughout history; yet there remains much to be understood about these practices of design, their underlying cognitive mechanisms, and ...
Katherine K. Fu +3 more
semanticscholar +1 more source
, 2002 We generalize an analogy between rotating and stratified shear flows. This analogy is summarized in Table 1. We use this analogy in the unstable case (centrifugally unstable flow v.s.
Dubrulle, B., Hersant, F.
core +1 more source
FEBS Open Bio, EarlyView.Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold +11 more
wiley +1 more source
On some differences between number fields and function fields
, 2016 The analogy between the arithmetic of varieties over number fields and the arithmetic of varieties over function fields is a leading theme in arithmetic geometry. This analogy is very powerful but there are some gaps.
Gasbarri, Carlo
core
Logic-Based Analogical Reasoning and Learning
, 2020 Analogy-making is at the core of human intelligence and creativity with applications to such diverse tasks as commonsense reasoning, learning, language acquisition, and story telling.
Antić, Christian
core
Thermal Effects in the dynamics of disordered elastic systems
, 2008 Many seemingly different macroscopic systems (magnets, ferroelectrics, CDW, vortices,..) can be described as generic disordered elastic systems. Understanding their static and dynamics thus poses challenging problems both from the point of view of ...
A. Rosso +20 more
core +3 more sources
FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source