Results 81 to 90 of about 6,176 (187)

Mapping Causal Biology: Mendelian Randomization in the Era of Big Data

Med Research, EarlyView.
Mendelian randomization (MR) leverages genetic variants to mitigate confounding biases in causal inference. This review systematically maps MR's methodological evolution, highlights its expanding applications in epidemiology and drug target validation, and outlines future directions for overcoming current biases through dynamic, multi‐omics, and cross ...
Xuanlu Shen, Chunrun Qu, Zeyu Wang, Jinglin Zhou, Hongwei Liu, Yingjie Li, Bowei Liu, Hao Zhang, Nan Zhang, Jingwei Zhang, Quan Cheng   +10 more
wiley   +1 more source

Interpretable and extrapolation-stable model for predicting nanofluid thermal conductivity. [PDF]

Sci Rep
Zinhom E, Radwan SS, Elmasry A, Sharaf MAM, Nassar MM.   +4 more
europepmc   +1 more source

A highly accurate numerical method for solving boundary value problem of generalized Bagley‐Torvik equation

Mathematical Methods in the Applied Sciences, EarlyView.
A highly accurate numerical method is given for the solution of boundary value problem of generalized Bagley‐Torvik (BgT) equation with Caputo derivative of order 0<β<2$$ 0<\beta <2 $$ by using the collocation‐shooting method (C‐SM). The collocation solution is constructed in the space Sm+1(1)$$ {S}_{m+1}^{(1)} $$ as piecewise polynomials of degree at ...
Suzan Cival Buranay, Mtema James Chin, Nazim I. Mahmudov   +2 more
wiley   +1 more source

Spatial Distribution of Topmouth Gudgeonis <i>Pseudorasbora parva</i> Under Climate Change by Ensemble Models. [PDF]

Ecol Evol
Li H, Sun W, Xiong W, Ju T, Wang W, Tang L, Wang Z, Gao X, Pan L, Dong X, Peng Y.   +10 more
europepmc   +1 more source

A Simple, Dynamic Geometric Phantom for MRI and CT Reconstruction Pipelines: Beyond Shepp–Logan

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT A customizable, dynamic geometric phantom was developed to bridge the gap between simplistic static phantoms and highly realistic, complex 4D solutions. The phantom enables initial testing, helps detect implementation errors, and supports quantitative evaluation of new dynamic acquisition and reconstruction methods.
Tamás Hakkel, Noémi Kovács, József Sinkó, Domokos Máthé, Krisztián Szigeti   +4 more
wiley   +1 more source

Intercept Estimation of Semi-Parametric Joint Models in the Context of Longitudinal Data Subject to Irregular Observations. [PDF]

Biom J
Ledesma L, Pullenayegum E.
europepmc   +1 more source

Deep Learning‐Based Dynamic Segmentation of the Left Atrium in 4D Flow MRI

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To design a deep learning pipeline for automated, time‐resolved segmentation of the left atrium (LA) from 4D flow MRI data. Methods We studied 100 individuals including 65 patients with atrial fibrillation (AF) and 35 healthy subjects (HS) resulting in 2530 4D flow MRI time‐volumes acquired in different centers and scanners.
Jonas Leite, Tom Da‐Silva Faria, Marie Shannon Soulez, Khaoula Bouazizi, Perrine Marsac, Elie Mousseaux, Jérôme Lamy, Moussa Gueda Moussa, Olivier Piot, Jacques Feignoux, Daniel Giese, Nicolas Badenco, Estelle Gandjbakhch, Alban Redheuil, Mikaël Laredo, Emilie Bollache, Nadjia Kachenoura   +16 more
wiley   +1 more source

Home and away: allometry and climate drive morphology of European rabbits in their native and introduced range

Oikos, EarlyView.
Climatic conditions shape phenotypic evolution by driving adaptations that optimise organismal function. Invasive species provide valuable systems to study these processes, as they often encounter novel climatic conditions in their introduced ranges. The European rabbit Oryctolagus cuniculus, native to the Iberian Peninsula, has established populations
Rishab Pillai, Natasha Lee Hiotis, Christine Böhmer, Cécile Callou, Thomas J. Nelson, Irina Ruf, Thomas J. Sanger, Julia Schaar, Kévin Le Verger, Madeleine Geiger, Brian Kraatz, Emma Sherratt   +11 more
wiley   +1 more source

Bayesian probabilistic projections of proportions with limited data: An application to subnational contraceptive method supply shares. [PDF]

PLoS One
Comiskey H, Cahill N, Alkema L, Frazier DT, Maneesoonthorn W.   +4 more
europepmc   +1 more source

The interacting effects of precipitation and microhabitat on non‐native seed predation are contingent on temporal dynamics

Oikos, EarlyView.
Understanding how different drivers of global change interact to shape ecological processes remains a major challenge in ecology. Climate change is reshuffling the interactions that structure communities, with major implications for biological invasions.
Mariana C. Chiuffo, Agostina Torres, Mauro N. Tammone, Martin A. Nuñez, Mariano A. Rodriguez‐Cabal   +4 more
wiley   +1 more source