Results 231 to 240 of about 72,747,221 (383)

'Better sleep, better wellbeing': Qualitative process evaluation of a hybrid, digital cognitive behavioural therapy programme for employees with sleep and emotion regulation problems. [PDF]

Br J Health Psychol
Hurley-Wallace A, Fletcher S, Moukhtarian TR, Patel K, Payne A, Jackson T, Toro C, Daly G, Russel S, Walasek L, Tang NKY, Meyer C.   +11 more
europepmc   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Hybrid Revascularization Approach Using Robot-Assisted Bilateral Internal Mammary Artery Grafting. [PDF]

Braz J Cardiovasc Surg
Issa HMN, Matar L, Shuster A, Athayde G, Ferreira L, Bucek M, Romanelli P, Centenaro DF, Hornestam JF, Issa AMN, Glineur D.   +10 more
europepmc   +1 more source

Analysis of Educational Quality, a Goal of Education for All Policy

, 2019
Rehaf Madani
openalex   +2 more sources

Efficacy of pancreatic enzyme replacement therapy in chronic pancreatitis: systematic review and meta-analysis [PDF]

, 2016
Daniel de la Iglesia, Wei Huang, Peter Szatmary, Iria Bastón‐Rey, Jaime González-López, Guillermo Prada-Ramallal, Rajarshi Mukherjee, Quentin Nunes, J. Enrique Domínguez‐Muñoz, Robert Sutton   +9 more
openalex   +1 more source

QIIME allows analysis of high-throughput community sequencing data

Nature Methods, 2010
J. Caporaso, Justin Kuczynski, Jesse Stombaugh, K. Bittinger, F. Bushman, E. Costello, N. Fierer, Antonio González Peña, Julia Goodrich, J. Gordon, G. Huttley, S. Kelley, D. Knights, J. Koenig, R. Ley, C. Lozupone, Daniel McDonald, B. Muegge, M. Pirrung, Jens Reeder, Joel R. Sevinsky, P. Turnbaugh, William Walters, Jeremy Widmann, Tanya Yatsunenko, Jesse R. Zaneveld, R. Knight   +26 more
semanticscholar   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Comparing masked and traditional visual analysis of multiple-baseline designs. [PDF]

J Appl Behav Anal
Wolfe K, Dowdy A, Ferron JM, Li R.
europepmc   +1 more source

The Microbiome Stress Project: Toward a Global Meta-Analysis of Environmental Stressors and Their Effects on Microbial Communities [PDF]

, 2019
Jennifer D. Rocca, Marie Simonin, Joanna R. Blaszczak, Jessica G. Ernakovich, Sean M. Gibbons, Firas S. Midani, Alex Washburne   +6 more
openalex   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source