Deficiency of the Synaptic Adhesion Protein Leucine-Rich Repeat Transmembrane Protein 4 Like 1 Affects Anxiety and Aggression in Zebrafish. [PDF]
Tatzl E+7 more
europepmc +1 more source
Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer
We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas+15 more
wiley +1 more source
A Novel Method to Determine the Carbon Isotopic Composition of Inositol Hexaphosphate (Phytate) in Soil by Gas Chromatography-Combustion-Isotope Ratio Mass Spectrometry. [PDF]
Sarangi V, Spohn M.
europepmc +1 more source
Cancer stem cells are associated with aggressive disease, but a deep characterization of such markers is lacking in endometrial cancer. This study uses imaging mass cytometry to explore putative cancer stem cell markers in endometrial tumors and corresponding organoid models.
Hilde E. Lien+7 more
wiley +1 more source
Rethinking Vulnerability: Using Factor Analysis to Assess Census Tract-Level Vulnerability. [PDF]
Jurecka C+6 more
europepmc +1 more source
Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park+6 more
wiley +1 more source
Construction of a novel prognostic model based on lncRNAs-related to DNA damage repair for predicting the prognosis of clear cell renal cell carcinoma. [PDF]
Chen P, Li J, Tian R.
europepmc +1 more source