Results 271 to 280 of about 62,999,708 (406)

The Phyre2 web portal for protein modeling, prediction and analysis

Nature Protocols, 2015
L. Kelley, Stefans Mezulis, C. M. Yates, Mark N. Wass, M. Sternberg   +4 more
semanticscholar   +1 more source

Session Law 81-113 [PDF]

, 1981
House of Representatives, Florida Senate &
core   +6 more sources

Stochastic variation in the FOXM1 transcription program mediates replication stress tolerance

Molecular Oncology, EarlyView.
Cellular heterogeneity is a major cause of drug resistance in cancer. Segeren et al. used single‐cell transcriptomics to investigate gene expression events that correlate with sensitivity to the DNA‐damaging drugs gemcitabine and prexasertib. They show that dampened expression of transcription factor FOXM1 and its target genes protected cells against ...
Hendrika A. Segeren, Kathryn A. Wierenga, Frank M. Riemers, Elsbeth A. van Liere, Bart Westendorp   +4 more
wiley   +1 more source

Combining treatment effects from mixed populations in meta-analysis: a review of methods. [PDF]

BMC Med Res Methodol
Wheaton L, Gsteiger S, Hubbard S, Bujkiewicz S.   +3 more
europepmc   +1 more source

Targeting PRAME directly or via EZH2 inhibition overcomes retinoid resistance and represents a novel therapy for keratinocyte carcinoma

Molecular Oncology, EarlyView.
The study evaluated the function and therapeutic implications of PRAME in basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). The findings demonstrate that PRAME impairs keratinocyte differentiation pathways. Furthermore, PRAME impairs anticancer response to retinoid compounds in BCC and SCC cells.
Brandon Ramchatesingh, Amelia Martinez Villarreal, Philippe Lefrançois, Jennifer Gantchev, Sriraam Sivachandran, Samy Abou Setah, Ivan V. Litvinov   +6 more
wiley   +1 more source

Structuring data analysis projects in the Open Science era with Kerblam! [PDF]

F1000Res
Visentin L, Munaron L, Ruffinatti FA.
europepmc   +1 more source

Role of Big Data in Cardiovascular Research

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
William S. Weintraub
doaj   +1 more source

Farm Management Analysis

, 1953
John A. Hopkin, Lawrence A. Bradford, Glenn L. Johnson   +2 more
openalex   +2 more sources

CircCCNB1 inhibits vasculogenic mimicry by sequestering NF90 to promote miR‐15b‐5p and miR‐7‐1‐3p processing in nasopharyngeal carcinoma

Molecular Oncology, EarlyView.
CircCCNB1 expression is down‐regulated in nasopharyngeal carcinoma (NPC); thus, less NF90 protein is bound to circCCNB1 and more binds to pri‐miRNAs, blocking their (pri‐miRNAs) binding to DGCR8 and inhibiting the processing and generation of miR‐15b‐5p/miR‐7‐1‐3p. Furthermore, decreased miR‐15b‐5p/miR‐7‐1‐3p promotes the expression of the target genes
Chunmei Fan, Fenghua Tan, Jie Wu, Zhaoyang Zeng, Wenjia Guo, He Huang, Wei Xiong   +6 more
wiley   +1 more source

Integrative analysis of mitochondrial-related gene profiling identifies prognostic clusters and drug resistance mechanisms in low-grade glioma. [PDF]

Discov Oncol
Chang X, Huang Y, Qu Y, Guo Y, Fan W, Zhen H.   +5 more
europepmc   +1 more source