Results 301 to 310 of about 46,394,056 (362)

Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren   +16 more
wiley   +1 more source

CINs of the cytoplasm: dissecting dsRNA signaling in chromosomal instability

open access: yesMolecular Oncology, EarlyView.
Micronuclei, formed during cell division in chromosomal instability settings, rupture and lead to the accumulation of immunogenic double‐stranded RNA in the cytoplasm, activating MAVS‐dependent interferon signaling and innate antitumor immunity.
Aglaia Skolariki   +2 more
wiley   +1 more source

Computational analysis of DEHP's oncogenic role in colorectal cancer. [PDF]

open access: yesDiscov Oncol
Zhu Z   +6 more
europepmc   +1 more source

Immunopipe: a comprehensive and flexible scRNA-seq and scTCR-seq data analysis pipeline. [PDF]

open access: yesNAR Genom Bioinform
Wang P   +11 more
europepmc   +1 more source

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