Results 31 to 40 of about 11,782,581 (248)

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

Analysis of 2021 pacific salmon fishing season

Известия ТИНРО, 2022
Analysis of 2021 Pacific salmon fishing season in the Far East of Russia is presented. It is based on data obtained from the Department of Anadromous Fish of Russia and the Far Eastern branches of the FSBSI «VNIRO», as well as the Far Eastern Territorial
S. L. Marchenko
doaj   +1 more source

Adherence to Protocol Recommendations for Children With Wilms Tumour in Two Consecutive Studies in the United Kingdom and Ireland—Does Variation Matter?

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait, R. Al‐Saadi, A. Lopez‐Cortes, K. Dzhuma, M. Oostveen, J. Brok, S. Irtan, M. Weeks, J. Bate, S. Baker, R. Williams, M. Powis, D. Saunders, O. Olsen, T. Watson, S. Shelmerdine, S. Vaidya, L. Howell, C. Duncan, G. M. Vujanic, C. Stiller, G. P. Balchin, T. Chowdhury, K. Pritchard‐Jones   +23 more
wiley   +1 more source

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson, Ingrid Winship, Gary Hammerschlag, Laura Scardamaglia   +3 more
wiley   +1 more source

Rating Assessment of the Competitiveness of Banks of the Republic of Belarus

Цифровая трансформация, 2022
The article proposes an original system of indicators, including financial performance indicators, digital development efficiency indicators, and bank competitiveness indicators. On the basis of systematic and integrated approaches, index methods and the
D. S. Shumsky, Ch. A. Zabrodskaya, O. A. Sosnovsky   +2 more
doaj   +1 more source

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski, Rebecca Ronsley, Shannon M. Stasi, Jeffrey Stevens, Erin R. Rudzinski, Christina M. Lockwood, Sarah E. S. Leary, Bonnie L. Cole, Michelle A. Ting, Vera Paulson   +9 more
wiley   +1 more source

Synthesis and antimicrobial activity of 3,5-R-4-(3-(5-nitrofuran-2-yl)-allylidenamino)-1-R1-4H-1,2,4-triazole halides derivatives

Zaporožskij Medicinskij Žurnal, 2015
Aim. A number of new 3,5-R-4-(3-(5-nitrofuran-2-yl)allylidenami-no)-1-R1-4H-1,2,4-triazole halides have been synthesized, the structure of synthesized compounds has been proved by modern physical-chemical methods. Methods and results.
T. S. Brytanova , A. S. Gotsulya, O. I. Panasenko, Ye. G. Knysh, N. S. Fedyunina   +4 more
doaj   +1 more source

Analysis under analysis [PDF]

Nature, 1989
Principal Component Analysis in Meteorology and Oceanography. By Rudolph W. Preisendorfer. Posthumously compiled and edited by Curtis D. Mobley. Elsevier: 1988. Pp.425. Dfl.210.
openaire   +1 more source

Preferences of Pediatric Patients and Their Caregivers for Chemotherapy‐Induced Nausea and Vomiting Control Endpoints: A Mixed Methods Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Although not always achieved, complete chemotherapy‐induced nausea and vomiting (CINV) control is the conventional goal of CINV prophylaxis. In this two‐center, mixed‐methods study, we sought to understand the preferences of adolescent patients and family caregivers for CINV control endpoints.
Haley Newman, Tadi Hondonga, Alison Berry, Caitlin Elgarten, Jason Freedman, Katelyn Oranges, Sara McDonough, Caroline Diorio, L. Lee Dupuis   +8 more
wiley   +1 more source

Development and Analysis of Six-Phase Synchronous Reluctance Motor for Increased Fault Tolerance Capabilities

Energies
This paper contains research on the development of a fault-tolerant six-phase synchronous reluctance motor (SynRM) based on the stator adopted from a general-purpose three-phase induction motor.
Cezary Jedryczka, Michal Mysinski, Wojciech Szelag   +2 more
doaj   +1 more source