Results 121 to 130 of about 206,415 (298)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

A study of Samuel Johnson's literary criticism : with special emphasis on the lives of the English poets

open access: yes, 1972
The impact of Johnson's beliefs and his statements of them have frequently been interpreted as excessively dogmatic. Indeed, some critics have chosen to view Johnson as an eccentric, the last defender of an obsolete neo-classical tradition.
Castellani, Joseph, 1931-
core  

SCIENCE: METHODS OF ANALYSIS IN LITERARY CRITICISM

open access: yes, 2021
Methods of analysis in Uzbek literature, at the same time, the scientist of literature I.In the literary criticism of Gafurov there is an opinion about the skill of using methods of ...
A.B.Kurbanova, Sh. N. Y. Akhmedova
core  

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Invisible Criticism Ralph Ellison and the American Canon

open access: yes
In 1952 Ralph Ellison won the National Book Award for his Kafkaesque and claustrophobic novel about the life of a nameless young black man in New York City.
Nadel, Alan.
core  

Corpus and Literary Criticism : An Analysis of Tess of the d'Urbervilles Using Concordancers [PDF]

open access: yes, 2007
Close reading is considered important in the criticism of English literature; however, in analyzing novels researchers should make a precise memo to record how and where certain words are used in the work.
Matsuda, Masako
core  

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Interior design criticism: Between excess and austerity [PDF]

open access: yes, 2003
In this paper, an analysis of a review article in an Australian design magazine is undertaken using a selected model of architectural criticism. While the model is found to be restrictive in facilitating exploration of fundamental philosophical issues in
Franz, Jill M.
core  

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