Results 181 to 190 of about 110,798 (311)

Avicenna on the Faculties of the Soul: A Critical Analysis with an Examination of Faḫr al-Dīn al-Rāzī’s Criticisms

Sajad Amirkhani, Keramat Varzdar
openalex   +2 more sources

“Hate Your Current Body, But Not Yourself”: A Reflexive Thematic Analysis of Dieting Behaviors, Body Ideals and Self-Criticism Among Queer Men Through Online Forums [PDF]

Harvey Regan, Michail Mantzios, Rebecca Keyte, Helen Egan   +3 more
openalex   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

The polarization of literary censorship in the U.S. [PDF]

PLoS One
Szetela A, Ji S, Macy MW.
europepmc   +1 more source

A Comparative Analysis of Semitic Rhetorical Analysis, Hermeneutics, and Biblical Criticism in Qur’anic Studies: Methodological Approaches and Challenges

Aqdi Rofiq Asnawi, Manzilah Manzilah
openalex   +1 more source

Judicious management of uncertain risks: I. Developments and criticisms of risk analysis and precautionary reasoning

, 2010
Charles Vlek
openalex   +2 more sources

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

LLMs outperform outsourced human coders on complex textual analysis. [PDF]

Sci Rep
Bermejo VJ, Gago A, Gálvez RH, Harari N.   +3 more
europepmc   +1 more source

A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy

Molecular Oncology, EarlyView.
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti, Giovanni Germano, Pietro Paolo Vitiello, Alberto Bardelli   +3 more
wiley   +1 more source

Effectiveness of implementing family involvement on patient outcomes in individuals with psychotic disorders: a pragmatic cluster randomised controlled trial. [PDF]

BMC Psychiatry
Norheim I, Pedersen R, Selle ML, Røssberg JI, Hestmark L, Heiervang KS, Ruud T, Åsholt VM, Hansson KM, Møller P, Fosse R, Kjus SHH, Romøren M.   +12 more
europepmc   +1 more source