Results 61 to 70 of about 2,783,365 (285)

Genetic algorithms and the analysis of SnIa data

open access: yes, 2010
The Genetic Algorithm is a heuristic that can be used to produce model independent solutions to an optimization problem, thus making it ideal for use in cosmology and more specifically in the analysis of type Ia supernovae data.
Alam U   +24 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Sequential selection of the k best out of nrankable objects [PDF]

open access: yesDiscrete Mathematics & Theoretical Computer Science, 2016
The objective of this paper is to find in a setting of n sequential observations of objects a good online policy to select the k bestof these n uniquely rankable objects.
F. Thomas Bruss, Guy Louchard
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Persisting randomness in randomly growing discrete structures: graphs and search trees [PDF]

open access: yesDiscrete Mathematics & Theoretical Computer Science, 2015
The successive discrete structures generated by a sequential algorithm from random input constitute a Markov chain that may exhibit long term dependence on its first few input values.
Rudolf Grübel
doaj   +1 more source

Average case analysis of marking algorithms [PDF]

open access: yes, 1984
The Lindstrom marking algorithm uses bounded workspace. Its time complexity is O(n^2) in all cases, but it has been assumed that the average case time complexity O(n lg n). It is proven that the average case time complexity is H(n^2).
Hirschberg, D. S., Larmore, L. L.
core   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Formal Analysis of Online Algorithms [PDF]

open access: yes, 2011
In [2], we showed how viewing online algorithms as reactive systems enables the application of ideas from formal verification to the competitive analysis of online algorithms. Our approach is based on weighted automata, which assign to each input word a cost in R≥0.
Benjamin Aminof   +2 more
openaire   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

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