Results 31 to 40 of about 993,426 (339)

Bias, precision and statistical power of analysis of covariance in the analysis of randomized trials with baseline imbalance: a simulation study

BMC Medical Research Methodology, 2014
BackgroundAnalysis of variance (ANOVA), change-score analysis (CSA) and analysis of covariance (ANCOVA) respond differently to baseline imbalance in randomized controlled trials.
B. Egbewale, Martyn Lewis, J. Sim
semanticscholar   +1 more source

Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani, Lakshmi Pillai, Reid D. Landes, Aliyah Glover, Shannon Doerhoff, Jennifer Kleiner, Mitesh Lotia, Rohit Dhall, Edgar Garcia‐Rill   +8 more
wiley   +1 more source

Brain structural covariance networks in obsessive-compulsive disorder: a graph analysis from the ENIGMA Consortium

Brain : a journal of neurology, 2020
In the largest brain structural covariance study of OCD to date, Yun et al. show a less segregated organization of structural covariance networks and a reorganization of brain hubs, including cingulate and orbitofrontal regions, in OCD.
J. Yun, P. Boedhoe, C. Vriend, N. Jahanshad, Y. Abe, S. Ameis, A. Anticevic, Paul D Arnold, M. Batistuzzo, Francesco Benedetti, J. Beucke, I. Bollettini, A. Bose, S. Brem, A. Calvo, Yuqi Cheng, K. Cho, V. Ciullo, S. Dallaspezia, Damiaan Denys, Jamie D. Feusner, J. Fouche, Mònica Giménez, P. Gruner, D. Hibar, M. Hoexter, Hao Hu, C. Huyser, Keisuke Ikari, N. Kathmann, C. Kaufmann, Kathrin Koch, L. Lázaro, C. Lochner, Paulo Marques, Rachel Marsh, I. Martínez-Zalacaín, D. Mataix-Cols, J. Menchón, L. Minuzzi, P. Morgado, P. Moreira, T. Nakamae, Tomohiro Nakao, J. Narayanaswamy, E. Nurmi, Joseph O’Neill, J. Piacentini, F. Piras, F. Piras, Y. Reddy, J. R. Sato, H. Simpson, N. Soreni, C. Soriano-Mas, G. Spalletta, Michael C. Stevens, P. Szeszko, D. Tolin, G. Venkatasubramanian, S. Walitza, Zhen Wang, G. V. van Wingen, Jian Xu, Xiufeng Xu, Qing Zhao, Odile3 A Dan J Premika S W Paul M Neda Chris Yoshinari St van den Heuvel Stein Boedhoe Thompson Jahanshad Vr, O. A. van den Heuvel, D. Stein, P. Boedhoe, P. Thompson, N. Jahanshad, C. Vriend, Y. Abe, S. Ameis, A. Anticevic, Paul D Arnold, M. Batistuzzo, Francesco Benedetti, J. Beucke, I. Bollettini, A. Bose, S. Brem, A. Calvo, Yuqi Cheng, K. Ik, K. Cho, V. Ciullo, S. Dallaspezia, Damiaan Denys, Jamie D. Feusner, J. Fouche, Mònica Giménez, P. Gruner, D. Hibar, M. Hoexter, Hao Hu, C. Huyser, Keisuke Ikari, N. Kathmann, C. Kaufmann, Kathrin Koch, Jun Soo Kwon, L. Lázaro, C. Lochner, Paulo Marques, Rachel Marsh, I. Martínez-Zalacaín, D. Mataix-Cols, J. Menchón, L. Minuzzi, Pedro Morgado, Pedro Moreira, T. Nakamae, Tomohiro Nakao, J. Narayanaswamy, E. L. Nurmi, Joseph O’Neill, J. Piacentini, F. Piras, F. Piras, Y. Reddy, J. R. Sato, H. Simpson, N. Soreni, C. Soriano-Mas, G. Spalletta, Michael C. Stevens, P. Szeszko, D. Tolin, G. Venkatasubramanian, S. Walitza, Zhen Wang, G. V. van Wingen, Jian Xu, Xiufeng Xu, J. Yun, Qing Zhao, P. Thompson, D. Stein, O. A. van den Heuvel, Jun Soo Kwon   +141 more
semanticscholar   +1 more source

Real‐World Performance of CSF Kappa Free Light Chains in the 2024 McDonald Criteria

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Kappa free light chains (KFLCs) in the cerebrospinal fluid (CSF) have a similar performance to CSF‐restricted oligoclonal bands (OCB) for multiple sclerosis (MS) diagnosis. To help with implementation, we set out to resolve several remaining uncertainties: (1) performance in a real‐world cohort and the 2024 McDonald criteria; (2 ...
Maya M. Leibowitz, Ryan Cooper, Stefania Kaninia, Kathryn I. Challis, Will Greenway, Maria Bonello, Mahmoud Elbahnasawi, Deborah T. Shode, Dominika Gajdasik, Victor Iliev, Alison M. E. Whitelegg, Ian Galea   +11 more
wiley   +1 more source

Simulations of Wide-Field Weak Lensing Surveys II: Covariance Matrix of Real Space Correlation Functions

, 2011
Using 1000 ray-tracing simulations for a {\Lambda}-dominated cold dark model in Sato et al. (2009), we study the covariance matrix of cosmic shear correlation functions, which is the standard statistics used in the previous measurements.
Albrecht, Albrecht, Cooray, Doré, Eisenstein, Hamana, Hicken, Hu, Jarvis, Kaiser, Komatsu, Mantz, Masahiro Takada, Masanori Sato, Miyazaki, Okumura, Perlmutter, Refregier, Riess, Sato, Seo, Spergel, Takahashi, Takahiko Matsubara, Takashi Hamana, Taruya, Van Waerbeke, Van Waerbeke, Vikhlinin, White   +29 more
core   +1 more source

Effects of Biological Sex and Age on Cerebrospinal Fluid Markers—A Retrospective Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cerebrospinal fluid (CSF) analysis is a key diagnostic tool for neurological diseases. To date, only a few studies have investigated in larger cohorts the effect of age and biological sex on diagnostic markers extracted from CSF. Methods For this retrospective observational study, 4163 CSF findings (2012–2020) were evaluated.
Isabel‐Sophie Hafer, Simon Faissner, Ralf Gold, Aiden Haghikia   +3 more
wiley   +1 more source

Knowledge-Aided Structured Covariance Matrix Estimator Applied for Radar Sensor Signal Detection

Sensors, 2019
This study deals with the problem of covariance matrix estimation for radar sensor signal detection applications with insufficient secondary data in non-Gaussian clutter. According to the Euclidean mean, the authors combined an available prior covariance
Naixin Kang, Zheran Shang, Qinglei Du
doaj   +1 more source

Association of CDKN2A/B Homozygous Deletion and Extent of Resection With Survival of Patients With WHO CNS5 Grade 4 Astrocytoma

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives WHO grade 4 astrocytomas are associated with poor prognosis, and their prognostic factors remain controversial. This study aimed to identify the prognostic factors and develop a management algorithm for these patients. Methods This study retrospectively included 151 CNS5 adult grade 4 astrocytomas from two medical centers.
Jiawei Cai, Guanglin Zhu, Qiu He, Chen Luo, Lingyun Zhuo, Xingfu Wang, Yiming Chen, Xiaoyong Chen, Wendong You, Jiaheng Xu, Yuanxiang Lin, Dezhi Kang, Shuai Wu, Zanyi Wu   +13 more
wiley   +1 more source

Does age in months influence Chinese Holstein dairy cow production performance after controlling for days in milk?

Frontiers in Veterinary Science
This study aimed to assess the impact of cows' age (in months) on production performance and evaluate the feasibility of using on-site data to inform precision agricultural practices on farms.
Lei Zhang, Cheng-Long Luo, Qi Mu, Jia-Cheng Liu, Chun-Fang Li, Ya-Bin Ma, Qi Su, Jun-Peng Zhang, Jian-Tao Li, Shu-Yi Zhang, Jian-Min Chai, Yao-Lu Zhao   +11 more
doaj   +1 more source

CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang, Yujie Liu, Fei Li, Xuelin Li, Lanlan Li, Jie Zhang, Yali Xu   +6 more
wiley   +1 more source