The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez +4 more
wiley +1 more source
Mapping Scientific Knowledge on Body Composition and Anthropometry in Soccer: A Bibliometric Analysis of the Last 35 Years (1990-2025). [PDF]
Paucar-Uribe JD +7 more
europepmc +1 more source
A minimal cellulosome‐like system in Cellulosilyticum lentocellum
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan +2 more
wiley +1 more source
Where is the lifestyle medicine in the Canadian undergraduate medical education curricula? A content analysis. [PDF]
Vaz D, Ibrahim S, Pikula A.
europepmc +1 more source
BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley +1 more source
Values-Led Coordination: Connect Coordination Victoria and the Establishment of a State-Wide Network of Family Carer Mental Health and Wellbeing Connect Centres. [PDF]
Phillips J +6 more
europepmc +1 more source
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen +8 more
wiley +1 more source
Readability of Online Informed Consent Forms for Implant-Based Breast Augmentation Across 6 Languages: Cross-Sectional Study. [PDF]
Kasperska K, Skrzypczak T, Gać P.
europepmc +1 more source
Retrieved relevant documents for document analysis
Identify, retrieve, analyze and compare international standards (e.g. WHO, IAHPS) and national regulations/guidelines/standards/strategies/policy documents that relate to palliative cancer rehabilitation.
openaire +1 more source

